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- Title
Testicular and prostatic function parameters in Wistar rats fed diets incorporated with 10% Vernonia amygdalina and Vernonia colorata leaves.
- Authors
Ijeh, Ifeoma Irene; Ekeleme-Egedigwe, Agatha C.; Opara, Benedict C.; Ahaiwe, Udochukwu
- Abstract
The study is aimed at investigating the effect of dietary incorporation at 10% of Vernonia amygdalina (VA) and Vernonia colorata (VC) on testicular and prostatic functions parameters in wistar rats. Fifteen male albino rats aged 16 weeks old were placed in three groups of five animals each. Group 1 and 2 was fed 10% dietary incorporation of Vernonia amygdalina (VA) and Vernonia colorata (VC) respectively. Group 3 served as the control and was fed normal rat chow. During three weeks of feeding, daily body weight was recorded. Serum testosterone, Prostate Specific Antigen (PSA) and Prostatic acid phosphatase (PACP) concentrations were determined using standard procedures. Serum testosterone significantly decreased (p<0.05) in the (VA and VC) groups compared to control. Prostate specific antigen (PSA) concentrations significantly (p<0.05) decreased in the group fed diets incorporated with VA and increased significantly in the groups fed diets incorporated with VC compared to the control group. Prostatic acid phosphatase (PACP) concentrations significantly (p<0.05) decreased in the VA group and significantly (p<0.05) increased in the experimental animals fed diet incorporated with Vernonia colorata (VC) compared to the control group. The testicular weight significantly (p<0.05) decreased in the test groups VA and VC relative to the control, while prostatic weight significantly (p<0.05) increased in VA and VC relative to control. These results suggest that Vernonia amygdalina and Vernonia colorata may have beneficial properties in the management of prostatic conditions.
- Subjects
VERNONIA; PROSTATE-specific antigen; FEED analysis
- Publication
Biokemistri, 2016, p144
- ISSN
0795-8080
- Publication type
Article