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- Title
The Structure and Activity of Double-Nitroimidazoles. A Mini-Review.
- Authors
Żwawiak, Justyna; Zaprutko, Lucjusz
- Abstract
Many interesting applications have been found for nitroimidazoles as therapeutic agents. Among others, some of these compounds can radiosensitize hypoxic tumor cells. The introduction of a second nitroimidazole ring to the molecule can improve the level of its pharmacological effect. The aim of this article is to overview the literature concerning active compounds that contain two nitroimidazole moieties in their structures.
- Subjects
NITROIMIDAZOLES; HYPOXEMIA; MOIETIES (Chemistry); STRUCTURE-activity relationships; RADIATION-sensitizing agents
- Publication
Scientia Pharmaceutica, 2018, Vol 86, Issue 3, p1
- ISSN
0036-8709
- Publication type
Article
- DOI
10.3390/scipharm86030030