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- Title
Exercise Training in Patients With Chronic Respiratory Failure Due to Kyphoscoliosis: A Randomized Controlled Trial.
- Authors
Cejudo, Pilar; López-Márquez, Isabel; López-Campos, Josė Luis; Márquez, Eduardo; de la Vega, Francisco; Barrot, Emilia; Ortega, Francisco
- Abstract
BACKGROUND: Research has provided evidence for the safety, feasibility, and efficacy of exercise training in patients with COPD. However, little is known about the impact of exercise training in patients with chronic respiratory failure due to kyphoscoliosis. We evaluated the effect of an exercise training program on exercise capacity, muscle strength, dyspnea, and quality-of-life indices in subjects with chronic respiratory failure due to kyphoscoliosis. METHODS: The 34 subjects were clinically stable, had been receiving nighttime home mechanical ventilation for ≥ 6 months, and were randomly assigned to the exercise group (n = 17) or the control group (n = 17). The exercise group conducted cycle and strength training on 3 non-consecutive days per week for 12 weeks. We measured pulmonary function, exercise capacity, peripheral muscle strength, dyspnea scores, and quality of life. RESULTS: Statistical analysis was carried out on the data from 16 subjects in the exercise group and in 11 subjects in the control group. Three of the lung-function parameters in the exercise group significantly changed: PaCO2 (P = .04), inspiratory pressure (P = .03), and expiratory pressure (P = .04); and endurance time (P = .002) and shuttle walk distance (P = .001) increased significantly. The exercise group had significantly greater improvements in peripheral muscle strength, dyspnea, and quality of life. CONCLUSIONS: In patients with chronic respiratory failure due to kyphoscoliosis, exercise training improved exercise capacity, peripheral muscle strength, dyspnea, and quality of life.
- Subjects
SPAIN; RESPIRATORY insufficiency treatment; SCOLIOSIS complications; CHRONIC diseases; DYSPNEA; EXERCISE therapy; KYPHOSIS; MUSCLE strength; HEALTH outcome assessment; QUALITY of life; RESEARCH funding; PULMONARY function tests; RESPIRATORY insufficiency; U-statistics; RANDOMIZED controlled trials; TREATMENT effectiveness; PRE-tests &; post-tests; ERGOMETRY; DATA analysis software; DESCRIPTIVE statistics; EXERCISE tolerance; DISEASE complications
- Publication
Respiratory Care, 2014, Vol 59, Issue 3, p375
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.02484