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- Title
Acupuncture modulates the gut microbiota in Alzheimer's disease: current evidence, challenges, and future opportunities.
- Authors
Long Yan; Hong Li; Yulin Qian; Qidi Liu; Shan Cong; Baomin Dou; Yu Wang; Meng Wang; Tao Yu
- Abstract
Alzheimer's disease, one of the most severe and common neurodegenerative diseases, has no effective cure. Therefore it is crucial to explore novel and effective therapeutic targets. The gut microbiota - brain axis has been found to play a role in Alzheimer's disease by regulating the neuro-immune and endocrine systems. At the same time, acupuncture can modulate the gut microbiota and may impact the course of Alzheimer's disease. In this Review, we discuss recent studies on the role of acupuncture on the gut microbiota as well current challenges and future opportunities of acupuncture as potential treatment for the prevention and treatment of Alzheimer's disease.
- Subjects
ALZHEIMER'S disease; GUT microbiome; ACUPUNCTURE; NEURODEGENERATION; ENDOCRINE system; APOLIPOPROTEIN E4; IRRITABLE colon
- Publication
Frontiers in Neuroscience, 2024, p01
- ISSN
1662-4548
- Publication type
Article
- DOI
10.3389/fnins.2024.1334735