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- Title
Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection.
- Authors
Mossong J; Hens N; Friederichs V; Davidkin I; Broman M; Litwinska B; Siennicka J; Trzcinska A; VAN Damme P; Beutels P; Vyse A; Shkedy Z; Aerts M; Massari M; Gabutti G; Mossong, J; Hens, N; Friederichs, V; Davidkin, I; Broman, M
- Abstract
We conducted a seroprevalence survey in Belgium, Finland, England & Wales, Italy and Poland on 13 449 serum samples broadly representative in terms of geography and age. Samples were tested for the presence of immunoglobulin G antibody using an enzyme immunoassay. The age-specific risk of infection was estimated using parametric and non-parametric statistical modelling. The age-specific risk in all five countries was highest in children aged 7-9 years and lower in adults. The average proportion of women of child-bearing age susceptible to parvovirus B19 infection and the risk of a pregnant women acquiring B19 infection during pregnancy was estimated to be 26% and 0.61% in Belgium, 38% and 0.69% in England & Wales, 43.5% and 1.24% in Finland, 39.9% and 0.92% in Italy and 36.8% and 1.58% in Poland, respectively. Our study indicates substantial epidemiological differences in Europe regarding parvovirus B19 infection.
- Publication
Epidemiology & Infection, 2008, Vol 136, Issue 8, p1059
- ISSN
0950-2688
- Publication type
journal article
- DOI
10.1017/s0950268807009661