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Imatinib mesylate (Gleevec) protects against streptozotocin-induced diabetes and islet cell death in vitro
- Published in:
- Cell Biology International, 2006, v. 30, n. 12, p. 1013, doi. 10.1016/j.cellbi.2006.08.006
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- Article
Mechanisms of Pancreatic B-Cell Degeneration during the Course of Insulin-dependent Diabetes Mellitus.
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- Acta Paediatrica, 1985, v. 74, n. s320, p. 7, doi. 10.1111/j.1651-2227.1985.tb10131.x
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- Article
ZBED6 counteracts high-fat diet-induced glucose intolerance by maintaining beta cell area and reducing excess mitochondrial activation.
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- Diabetologia, 2021, v. 64, n. 10, p. 2292, doi. 10.1007/s00125-021-05517-0
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- Article
Knock-down of ZBED6 in insulin-producing cells promotes N-cadherin junctions between beta-cells and neural crest stem cells in vitro.
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- Scientific Reports, 2016, p. 19006, doi. 10.1038/srep19006
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- Article
Co-Culture of Neural Crest Stem Cells (NCSC) and Insulin Producing Beta-TC6 Cells Results in Cadherin Junctions and Protection against Cytokine-Induced Beta-Cell Death.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061828
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- Article
Effects of Imatinib Mesylate (Gleevec) on Human Islet NFappaB Activation and Chemokine Production In Vitro.
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- PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024831
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- Publication type:
- Article
High Glucose Suppresses Human Islet Insulin Biosynthesis by Inducing miR-133a Leading to Decreased Polypyrimidine Tract Binding Protein-Expression.
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- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010843
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- Article
siRNA Produced by Recombinant Dicer Mediates Efficient Gene Silencing in Islet Cells.
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- Annals of the New York Academy of Sciences, 2005, v. 1040, n. 1, p. 114, doi. 10.1196/annals.1327.014
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- Article
Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.
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- Clinical Science, 2015, v. 128, n. 1, p. 17, doi. 10.1042/CS20130560
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- Article
Detailed transcriptome atlas of the pancreatic beta cell.
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- BMC Medical Genomics, 2009, v. 2, p. 1, doi. 10.1186/1755-8794-2-3
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- Publication type:
- Article
The importance of the ZBED6‐IGF2 axis for metabolic regulation in mouse myoblast cells.
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- FASEB Journal, 2020, v. 34, n. 8, p. 10250, doi. 10.1096/fj.201901321R
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- Article
The protein synthesis inhibitor brusatol normalizes high-fat diet-induced glucose intolerance in male C57BL/6 mice: role of translation factor eIF5A hypusination.
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- FASEB Journal, 2019, v. 33, n. 3, p. 3510, doi. 10.1096/fj.201801698R
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- Article
ZBED6 negatively regulates insulin production, neuronal differentiation, and cell aggregation in MIN6 cells.
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- FASEB Journal, 2019, v. 33, n. 1, p. 88, doi. 10.1096/fj.201600835R
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- Article
Amelioration of diabetes by imatinib mesylate (Gleevec): role of β-cell NF-κβ activation and anti-apoptotic preconditioning.
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- FASEB Journal, 2007, v. 21, n. 2, p. 618, doi. 10.1096-fj.06-6910com
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- Publication type:
- Article
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells.
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- 2008
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- journal article
Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets.
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- 2008
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- journal article
MAPK Kinase Kinase-1 Is Essential for Cytokine-Induced c-Jun NH<sub>2</sub>-Terminal Kinase and Nuclear Factor-ΚB Activation in Human Pancreatic Islet Cells.
- Published in:
- Diabetes, 2008, v. 57, n. 7, p. 1896, doi. 10.2337/db07-1670
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- Article
Improved Vascular Engraftment and Graft Function After Inhibition of the Angiostatic Factor Thrombospondin-1 in Mouse Pancreatic Islets.
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- Diabetes, 2008, v. 57, n. 7, p. 1870, doi. 10.2337/db07-0724
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- Article
Mechanisms of Pancreatic Β-cell Death in Type 1 and Type 2 Diabetes.
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- Diabetes, 2005, v. 54, p. S97, doi. 10.2337/diabetes.54.suppl_2.S97
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- Article
Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
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- 2005
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- journal article
Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment.
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- 1999
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- journal article
Beta-hydroxybutyrate increases reactive oxygen species in late but not in early postimplantation embryonic cells in vitro.
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- 1998
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- journal article
Efficient gene transfer to dispersed human pancreatic islet cells in vitro using adenovirus-polylysine/DNA complexes or polycationic liposomes.
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- 1996
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- journal article
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
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- 1991
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- journal article
Exhibition of specific alterations in activities and mRNA levels of rat islet glycolytic and mitochondrial enzymes in three different in vitro model systems for attenuated insulin release.
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- 1991
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- journal article
Influence of protease on inhibitory and stimulatory effects of interleukin 1 beta on beta-cell function.
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- 1991
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- journal article
Content of adenine nucleotide translocator mRNA in insulin-producing cells of different functional states.
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- 1989
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- journal article
Insulin production and glucose metabolism in isolated pancreatic islets of rats with NIDDM.
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- 1988
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- journal article
Use of liposomes to introduce substances into pancreatic islet cells.
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- 1988
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- journal article
Pharmacological Inhibition of NOX4 Improves Mitochondrial Function and Survival in Human Beta-Cells.
- Published in:
- Biomedicines, 2021, v. 9, n. 12, p. 1865, doi. 10.3390/biomedicines9121865
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- Article
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.
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- Clinical Science, 2021, v. 135, n. 19, p. 2243, doi. 10.1042/CS20210604
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- Article
The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro.
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- PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0204271
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- Article
GDF15 Protects Insulin-Producing Beta Cells against Pro-Inflammatory Cytokines and Metabolic Stress via Increased Deamination of Intracellular Adenosine.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 801, doi. 10.3390/ijms25020801
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- Article
Thrombospondin-1: an islet endothelial cell signal of importance for β-cell function.
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- 2011
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- Publication type:
- journal article
Thrombospondin-1: An Islet Endothelial Cell Signal of Importance for β-Cell Function.
- Published in:
- Diabetes, 2011, v. 60, n. 7, p. 1946, doi. 10.2337/db10-0277
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- Publication type:
- Article