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- Title
The Relevance of Mass Spectrometry Analysis for Personalized Medicine through Its Successful Application in Cancer "Omics".
- Authors
Ciocan-Cartita, Cristina Alexandra; Jurj, Ancuța; Buse, Mihail; Gulei, Diana; Braicu, Cornelia; Raduly, Lajos; Cojocneanu, Roxana; Pruteanu, Lavinia Lorena; Iuga, Cristina Adela; Coza, Ovidiu; Berindan-Neagoe, Ioana
- Abstract
Mass spectrometry (MS) is an essential analytical technology on which the emerging omics domains; such as genomics; transcriptomics; proteomics and metabolomics; are based. This quantifiable technique allows for the identification of thousands of proteins from cell culture; bodily fluids or tissue using either global or targeted strategies; or detection of biologically active metabolites in ultra amounts. The routine performance of MS technology in the oncological field provides a better understanding of human diseases in terms of pathophysiology; prevention; diagnosis and treatment; as well as development of new biomarkers; drugs targets and therapies. In this review; we argue that the recent; successful advances in MS technologies towards cancer omics studies provides a strong rationale for its implementation in biomedicine as a whole.
- Subjects
INDIVIDUALIZED medicine; MASS spectrometry; CANCER; TARGETED drug delivery; ONCOLOGY
- Publication
International Journal of Molecular Sciences, 2019, Vol 20, Issue 10, p2576
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms20102576