We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Health care consequences of hospitalization with Clostrioides difficile infection: a propensity score matching study.
- Authors
Hirsch, Bruce E.; Williams, Myia S.; Stefanov, Dimitre G.; Lesser, Martin L.; Pappas, Karalyn; Iglio, Thomas; Gordon, Craig; Pekmezaris, Renee
- Abstract
<bold>Background: </bold>Clostridiodies difficile infection (CDI) has been characterized by the Center for Disease Control and Prevention (CDC) as an urgent public health threat and a major concern in hospital, outpatient and extended-care facilities worldwide.<bold>Methods: </bold>A retrospective cohort study of patients aged ≥ 18 hospitalized with CDI in New York State (NYS) between January 1, 2014-December 31, 2016. Data were extracted from NY Statewide Planning and Research Cooperative (SPARCS) and propensity score matching was performed to achieve comparability of the CDI (exposure) and non-CDI (non-exposure) groups. Of the 3,714,486 hospitalizations, 28,874 incidence CDI cases were successfully matched to 28,874 non-exposures.<bold>Results: </bold>The matched pairs comparison demonstrated that CDI cases were more likely to be readmitted to the hospital at 30 (28.26% vs. 19.46%), 60 (37.65% vs. 26.02%), 90 (42.93% vs. 30.43) and 120 days (46.47% vs. 33.74), had greater mortality rates at 7 (3.68% vs. 2.0%) and 180 days (20.54% vs. 11.96%), with significant increases in length of stay and total hospital charges (p < .001, respectively).<bold>Conclusions: </bold>CDI is associated with a large burden on patients and health care systems, significantly increasing hospital utilization, costs and mortality.
- Subjects
NEW York (N.Y.); NEW York (State); PROPENSITY score matching; CENTERS for Disease Control &; Prevention (U.S.); MEDICAL care; HOSPITAL care; LENGTH of stay in hospitals; HOSPITAL charges
- Publication
BMC Infectious Diseases, 2022, Vol 22, Issue 1, p1
- ISSN
1471-2334
- Publication type
journal article
- DOI
10.1186/s12879-022-07594-x