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- Title
Actin and myosin I in the nucleus: what next?
- Authors
de Lanerolle, Primal; Johnson, Terazina; Hofmann, Wilma A
- Abstract
Several recent publications have demonstrated the importance of nuclear actin and nuclear myosin I in transcription. Here we review these publications and their implications. In addition, we discuss some important issues that should be addressed to gain a more comprehensive understanding of how these traditionally 'cytoplasmic' proteins are involved in transcription. We propose highly speculative models and mechanisms solely to stimulate thought and experimentation in this area.
- Subjects
ACTIN; ACTOMYOSIN; MYOSIN; GLOBULINS; MUSCLE proteins; CYTOPLASM
- Publication
Nature Structural & Molecular Biology, 2005, Vol 12, Issue 9, p742
- ISSN
1545-9993
- Publication type
Article
- DOI
10.1038/nsmb983