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- Title
Active deep brain stimulation during MRI: A feasibility study.
- Authors
J.-C. Georgi; C. Stippich; V.M. Tronnier; S. Heiland
- Abstract
The goal of this study was to evaluate the feasibility of active deep brain stimulation (DBS) during the application of standard clinical sequences for functional MRI (fMRI) in phantom measurements. During active DBS, we investigated induced voltage, temperature at the electrode tips and lead, forces on the electrode and lead, consequences of defective leads and loose connections, proper operation of the neurostimulator, and image quality. Sequences for diffusion- and perfusion-weighted imaging, fMRI, and morphologic MRI were used. The DBS electrode and lead were placed in a NaCl solution-filled phantom. The results indicate that there are severe potential hazards for patients. Strong heating, high induced voltage, and even sparking at defects in the connecting cable could be observed. However, it was demonstrated that under certain conditions, safe MR examinations during active DBS are feasible. Certain safety precautions are recommended in this report. Magn Reson Med 51:380388, 2004. © 2004 Wiley-Liss, Inc.
- Subjects
BRAIN stimulation; NEURAL stimulation; MAGNETIC resonance imaging; DIAGNOSTIC imaging; ELECTROPHYSIOLOGY
- Publication
Magnetic Resonance in Medicine, 2004, Vol 51, Issue 2, p380
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.10699