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- Title
Postarthroscopy analgesia using intraarticular levobupivacaine and intravenous dexketoprofen trometamol.
- Authors
Sahin, Sevtap; Memiş, Dilek; Celik, Erkan; Sut, Necdet; Sahin, Sevtap Hekimoglu; Memiş, Dilek
- Abstract
<bold>Purpose: </bold>The aim of this prospective study was to determine the efficacy of intraarticular levobupivacaine with and without intravenous dexketoprofen trometamol for postarthroscopy analgesia.<bold>Methods: </bold>Sixty patients who underwent arthroscopic knee surgery were randomly assigned to three treatment groups. When the surgical procedure was completed, patients received the following treatments: group I (n = 20) patients received 20 mL intraarticular normal saline and 2 mL intravenous dexketoprofen trometamol (50 mg); group II (n = 20) patients received 20 mL intraarticular 0.5 % levobupivacaine (100 mg) and 2 mL intravenous normal saline; and group III (n = 20) patients received 20 mL intraarticular 0.5 % levobupivacaine (100 mg) and 2 mL intravenous dexketoprofen trometamol (50 mg). The visual analogue scale (VAS) was used, and the total analgesic consumption was assessed at 1, 2, 4, 6, 12, and 24 h post-operatively.<bold>Results: </bold>The VAS scores at 1, 2, 4, 6, 12, and 24 h post-operatively were significantly increased in group I and group II compared with group III (p < 0.05). The average VAS score during the first 24 h post-operatively was significantly lower in group III than in group I and group II (p < 0.001). Total meperidine consumption was significantly lower in group III than in groups I and II (p < 0.001).<bold>Conclusion: </bold>Intraarticular levobupivacaine with adjuvant intravenous dexketoprofen trometamol administration provided better pain relief and less analgesic requirement after arthroscopic knee surgery during the first 24 h than that induced by dexketoprofen alone or levobupivacaine intraarticular alone.<bold>Level Of Evidence: </bold>II.
- Subjects
NONSTEROIDAL anti-inflammatory agents; ANALGESIA; BUPIVACAINE; TROMETHAMINE (Drug); ARTHROSCOPY; THERAPEUTICS
- Publication
Knee Surgery, Sports Traumatology, Arthroscopy, 2015, Vol 23, Issue 12, p3516
- ISSN
0942-2056
- Publication type
journal article
- DOI
10.1007/s00167-014-3191-2