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- Title
Ultrastructural localization of carbonic anhydrase and its possible role in the endolymphatic sac.
- Authors
Takumida, Masaya; Bagger-Sjöbäck, Dan; Rask-Anderseri, Helge; Takumida, M; Bagger-Sjöbäck, D; Rask-Andersen, H
- Abstract
Carbonic anhydrase was detected histochemically in the guinea pig endolymphatic sac. The enzyme reaction was positive in both light and dark epithelial cells. In the former, the reaction product was found in the cytoplasm, especially around the intracytoplasmic vesicles and vacuoles. Reaction product was found in the basolateral infoldings as well. The dark epithelial cells also displayed carbonic anhydrase activity in the cytoplasm as well as in the lysosome-like bodies. It is suggested that this enzyme may be involved in (1) ionic or fluid regulation of the endolymph, (2) otoconia metabolism, and (3) phagocytotic activities.
- Subjects
ANIMAL experimentation; CARBONIC anhydrase; COMPARATIVE studies; CYTOCHEMISTRY; CYTOPLASM; ELECTRON microscopy; GUINEA pigs; INNER ear; RESEARCH methodology; MEDICAL cooperation; PHAGOCYTOSIS; RESEARCH; VESTIBULAR apparatus; WATER-electrolyte balance (Physiology); EVALUATION research; ENDOLYMPHATIC sac
- Publication
ORL, 1988, Vol 50, Issue 3, p170
- ISSN
0301-1569
- Publication type
journal article
- DOI
10.1159/000275986