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- Title
Inverstigation of corneal and lens densitometry in eyes of patients with primary myelofbrosis.
- Authors
Yilmaz, Ugur; Cagliyan, Gulsum Akgun; Akbay, Burak
- Abstract
Aim: To investigate the corneal-lens densitometry and endothelial cells of Primary myelofbrosis patients. Materials and Methods: We evaluated 49 eyes of 49 primary myelofbrosis patients on follow up in hematology clinic and compared to 46 eyes of 46 age and sex-matched control group . The Scheimpflug images of 90-270 degrees by Pentacam HR (Oculus Optikgeräte GmbH, Wetzlar, Germany) were used for measurement. After pupil dilatation, the corneal apex was marked by pentacam automatically and the diameter of central 6 mm around marked point was analyzed. PNS (Pentacam Nuclear Staging) software was used for densitometric analysis of the lens from a cylindrical region in the nucleus center. Specular Microscope CEM-530 (Nidek, Japan) was used for endothelial cell analysis. Results: There was no statistically signifcant difference between groups for age and gender(Table1). Corneal density and corneal volume were higher in the patient group but it was not statistically signifcant (respectively p=0.390, p=0.078). Lens density was found as statistically signifcantly higher in the patient group compared to the control group(p<0.001). For the corneal endothelial analysis by specular microscopy, there was no statistically signifcant difference for cell density, the coeffcient of variant and endothelial hexagonality (respectively, p=0.546, 0.671, 0.103). Conclusion: Primary myelofbrosis does not affect corneal densitometry and corneal endothelial cells. However, there is a higher lens densitometric measurement in Primary myelofbrosis compared to the control healthy group.
- Subjects
DENSITOMETRY; MYELOFIBROSIS; COMPUTER software; SPECULAR microscopy; ENDOTHELIAL cells
- Publication
Annals of Medical of Research, 2021, Vol 28, Issue 5, p1015
- ISSN
2636-7688
- Publication type
Article
- DOI
10.5455/annalsmedres.2020.04.398