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- Title
IgG4-related disease presenting with cholangitis mimicking cholangiocarcinoma: a case report with a literature review.
- Authors
Mansoorian, Mohsenreza; Ahmadi, Seyyed Amir Yasin; Sabouri, Shahriar
- Abstract
Introduction. IgG4-related disease (IgG4-RD) is currently known as a unique progressive immune-mediated disease creating tumor-like fibrotic masses in different organs of the human body. Case presentation. We report a 23-year-old woman who presented with acute abdominal pain, icterus, and fever. A biliary stricture aroused suspicion of cholangiocarcinoma. In addition, some colon masses were observed, which were suspected to be mucinous carcinoma with appendix origin. The patient underwent a major surgery consisting of cholecystectomy, hepaticojejunostomy, and right hemicolectomy. The post-surgical pathology report for all the lesions and masses was IgG4-RD. Conclusion. The biliary lesion was IgG4-related sclerosing cholangitis. We concluded that IgG4-RD was a rare but important differential diagnosis for solitary or multiple masses and biliary lesions.
- Subjects
CHOLANGIOCARCINOMA; HEMICOLECTOMY; ABDOMINAL pain; CHOLECYSTECTOMY; HUMAN body
- Publication
Oncology in Clinical Practice (2450-1654), 2022, Vol 18, Issue 5, p349
- ISSN
2450-1654
- Publication type
Article
- DOI
10.5603/OCP.2022.0038