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- Title
A Brain Function Study of Combining Amplitude of Low Frequency Fluctuations and Degree Centrality in Patients with High Myopia.
- Authors
ZHANG Xiaopan; YANG Fan; JIN Xuemin; CHENG Jingliang; WEN Baohong
- Abstract
To explore the abnormal changes of local brain function in patients with high myopia (HM) during the resting state by a combining amplitude of low frequency fluctuations (ALFF) and degree centrality (DC) method. A total of 45 HM patients were selected as the HM group, and 46 subjects with normal binocular vision were selected as the control group. All subjects underwent a resting-state functional magnetic resonance imaging scan. Altered local brain function was analyzed by using combined ALFF and DC. Comparison between groups was performed by two-sample t test based on voxel level. The results showed that compared with the control group, (1) there were widespread ALFF differences between groups throughout the left Inferior frontal gyms, orbital part; right calcarine fissure and surrounding cortex; right anterior cingulate and paracingulate gyri; left thalamus; left inferior parietal, but supramarginal and angular gyri; right inferior parietal, but supramarginal and angular gyri and left paracentral lobule (P<0.05) ; (2) there were widespread DC differences between groups throughout the right inferior temporal gyrus; left inferior temporal gyrus; right anterior cingulate and paracingulate gyri; left superior frontal gyrus, medial orbital; left calcarine fissure and surrounding cortex; right fusiform gyrus; left inferior parietal, but supramarginal and angular gyri and left paracentral lobule (P< 0.05). The combination of low-frequency amplitude and degree centrality has high application value in the judgment of brain neuronal activity and brain functional network changes in HM patients.
- Subjects
FUSIFORM gyrus; FUNCTIONAL magnetic resonance imaging; TEMPORAL lobe; CINGULATE cortex; MYOPIA; BINOCULAR vision
- Publication
Imaging Science & Photochemistry, 2023, Vol 41, Issue 5, p230
- ISSN
1674-0475
- Publication type
Article
- DOI
10.7517/issn.1674-0475.230601