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- Title
Proximal flow to middle cerebral artery is associated with higher thrombus density in terminal internal carotid artery occlusion.
- Authors
Pikija, Slaven; Magdic, Jozef; Killer‐Oberpfalzer, Monika; Florea, Cristina; Hauer, Larissa; Novak, Helmut F.; McCoy, Mark R.; Sellner, Johann
- Abstract
Proximal collaterals may determine the composition of occluding thrombi in acute ischemic stroke ( AIS) in addition to source, hematocrit, time, and medication. Here, we performed a retrospective study of 39 consecutive patients with radiological evidence of I-, L-, and T-type terminal internal carotid artery occlusion. Middle cerebral artery ( MCA) thrombus density was assessed on noncontrast enhanced CT and proximal collaterals on CT angiography. In patients with presence of proximal collaterals to the MCA we detected more hyperdense clots ( P = 0.003) and a higher frequency of leptomeningeal collaterals ( P = 0.008). We expand the spectrum of factors that potentially determine clot perviousness and evolution of ischemic stroke.
- Subjects
CEREBRAL arterial diseases; CEREBRAL artery surgery; THROMBIN regulation; THROMBIN; ANGIOGRAPHY; THERAPEUTICS
- Publication
Annals of Clinical & Translational Neurology, 2017, Vol 4, Issue 7, p517
- ISSN
2328-9503
- Publication type
Article
- DOI
10.1002/acn3.429