We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
İsoindolsübstitüe-kalkon Türevlerine İyot Katalizli Tiyofenol Katılması.
- Authors
Budak, Yakup; Çakır, Ahmet Doğan; Özbek, Oğuz; Gürdere, Meliha Burcu; Ceylan, Mustafa
- Abstract
Chalcone and isoindol derivatives possess significant biological activities. Also, ıt is known that hybrid molecules carrying these two units in the same structure show biological activity. In addition, -mercaptans are used as the starting material for the synthesis of some bioactive compounds. In this work, new ß-mercapto carbonyl compounds (5a-j), (3aR,4S,7R,7aS)-2-(4-(3-(phenylthio)-3-(aryl)pyridyl)aminocarbonylpropanol) phenyl)-3a,4,7,7a-tetrahydro-1H-7-methanoisoindole-1,3(2H)-dione), were obtained by molecular iodine-catalyzed addition of thiophenol to isoindol substituted chalcone derivatives (3a-j) in high yields. The structures of the obtained new compounds were clarified by 1H-NMR, 13C-NMR, FT-IR and Elemental Analysis spectroscopic methods.
- Publication
Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi, 2020, Vol 7, Issue 1, p161
- ISSN
2458-7575
- Publication type
Article
- DOI
10.35193/bseufbd.721691