We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Polimorfismos genéticos e o insucesso dos implantes dentários: estudo piloto.
- Authors
TEIXEIRA, Camila Epitácio Cravo; MATHEUS, Tibério César Uchôa; de SOUZA, Paulo Roberto Eleutério; DONOS, Nikos; CIMÕES, Renata
- Abstract
Objective: To investigate the relationship between genetic polymorphisms related to cytokines in bone remodeling osteoprotegerin (OPG) and receptor activator of nuclear factor kappa β ligand (RANKL). It also aims to relate the presence of OPG and RANKL polymorphisms with clinical failure of dental implants over time and to determine which combinations of OPG and RANKL polymorphisms are associated with failure of dental implants. Methods: Twenty patients of both sexes, over eighteen years, rehabilitated with thirty-four dental implants were evaluated during 24 months after implant-supported crown placement. After clinical and radiographic examination, patients were included in a failure group if one or more of the following criteria were identified: mobility, persistent subjective complaints, recurrent peri-implantitis with suppuration, continuous radiolucency around the implant, probing depth = 5 mm and bleeding on probing. Peripheral blood was collected for analysis of cytokine OPG and RANKL polymorphisms by polymerase chain reaction (PCR). Results: There were no statistically significant differences between the failure group in relation to genotypes OPG and RANKL. Conclusion: OPG and RANKL polymorphisms did not influence dental implants failure in the investigated sample.
- Publication
Dental Press Implantology, 2014, Vol 8, Issue 4, p68
- ISSN
2237-650X
- Publication type
Article
- DOI
10.14436/2237-650X.8.4.068-078.oar