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- Title
REVIEW ARTICLE Resistin: an adipocyte-derived hormone. Has it a role in diabetes and obesity?
- Authors
Rea, Rustam; Donnelly, Richard
- Abstract
The article focuses on the role of resistin, an adipocyte-derived hormone in diabetes and obesity. The discovery of resistin, together with other adipocyte- derived hormones, has prompted intense research into the role of fat-derived mediators in obesity-induced insulin resistance and type 2 diabetes. The discovery and functional importance of resistin were first high-lighted in the journal Nature in 2001. After that several follow-up studies have explored the cellular, physiological and clinical importance of resistin, but fundamental questions remain unclear and several inconsistencies have emerged.
- Subjects
FAT cells; INSULIN resistance; DIABETES complications; TYPE 2 diabetes; OBESITY; METABOLIC disorders
- Publication
Diabetes, Obesity & Metabolism, 2004, Vol 6, Issue 3, p163
- ISSN
1462-8902
- Publication type
Article
- DOI
10.1111/j.1462-8902.2004.00334.x