We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Review of Congenital Neurologic Malformations.
- Authors
Icenogle, Deborah A.; Kaplan, Allen M.
- Abstract
Congenital neurologic malformations present a difficult challenge to the clinician in regard to diagnosis, management, and prevention. The authors review normal ontogenesis and divide this complex process into three developmental phases: (1) induction. (2) cellular proliferation and migration, and (3) maturation of cellular organization, synaptic development, and myelin formation. A classification of malformations based on the timing of occurrence during the first and second stages of central nervous system development is presented. These disorders are described with particular attention to the clinical and diagnostic features. Various prenatal diagnostic screening tests are also reviewed in an attempt to identify the population at risk for congenital neurologic malformations.
- Subjects
NERVOUS system abnormalities; ONTOGENY; CELL proliferation; CELL migration; HUMAN abnormalities; DISEASE risk factors; DEVELOPMENTAL neurobiology
- Publication
Clinical Pediatrics, 1981, Vol 20, Issue 9, p565
- ISSN
0009-9228
- Publication type
Article
- DOI
10.1177/000992288102000903