We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sık seftriakson kullanımı ve safra kesesi taşı: yedi olgunun sunumu.
- Authors
Abuhandan, Mahmut; Karakaş, Ekrem; Çeçe, Hasan; Karakaş, Ömer; Çakmak, Alpay
- Abstract
Ceftriaxone is a third-generation cephalosporin antibiotic with potent antimicrobial activity, which is parenterally administered in the treatment of numerous infectious diseases. Transient formation of stone or sludge within gallbladder, which develops in the gallbladder lumen depending on the use of ceftriaxone and usually disappears spontaneously without causing any symptoms, is named pseudolithiasis. There have been clinical and experimental studies conducted in time, which addressed the chemical mechanism of pseudolithiasis, factors affecting its formation and disappearance, and its radiological progress. In this study, 7 patients were enrolled, who received intramuscular treatment of ceftriaxone more than 3 times for at least five days and hence developed gallstones. Gallstones of patients, who were followed-up with weekly ultrasonographic examinations, were observed to have spontaneously vanished within 3-6 weeks. To conclude, we intended to emphasize that gallstone formation developed in patients receiving ceftriaxone is an anticipated complication and resolves spontaneously without any treatments, and thus that any unnecessary medications and surgical interventions should be avoided.
- Subjects
GALLSTONES; CASE studies; CEFTRIAXONE
- Publication
Journal of Harran University Medical Faculty / Harran Üniversitesi Tıp Fakültesi Dergisi, 2012, Vol 9, Issue 3, p145
- ISSN
1304-9623
- Publication type
Article