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- Title
4-(Dimethylamino)pyridine as an Efficient Catalyst for One-Pot Synthesis of 1,4- Pyranonaphthoquinone Derivatives via Microwave-Assisted Sequential Three Component Reaction in Green Solvent.
- Authors
Nguyen Ha Thanh; Hoang Thi Phuong; Le Nhat Thuy Giang; Nguyen Thi Quynh Giang; Nguyen Thi Thu Ha; Dang Thi Tuyet Anh; Vu Duc Cuong; Nguyen Van Tuyen; Phan Van Kiem
- Abstract
Novel 1,4-pyranonaphthoquinone derivatives were successfully synthesized via the microwave-assisted three-component reaction of 1,4-naphthoquinone, malononitrile, and various arylaldehydes in ethanol in the presence of 4-(dimethylamino)pyridine (DMAP) as a catalyst, and subsequently evaluated in terms of their antimicrobial and antifungal activities. This synthetic procedure has the notable advantages of environmental friendliness, short reaction time, good yield, and convenient operation.
- Subjects
CATALYST synthesis; PYRIDINE; SOLVENTS; MALONONITRILE; FRIENDSHIP
- Publication
Natural Product Communications, 2021, Vol 16, Issue 11, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X211053951