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- Title
PENILE ANO SCROTUM SWELLING IN JUVENILE DERMATOMYOSITIS.
- Authors
Sallum, Adriana Maluf Elias; Silva, Marco Felipe Castro; Michelin, Cíntia Maria; Duarte, Ricardo Jordão; Baroni, Ronaldo Hueb; Aikawa, Nádia Emi; Silva, Clovis Artur
- Abstract
Edema is a well-known feature of juvenile dermatomyositis (JDM). However, to our knowledge localized penile and scrotum swelling was not previously reported. During a 27-year period, 5,506 patients were followed up at the Pediatric Rheumatology Unit of our University Hospital and 157 patients (2.9%) had JDM. One of them (0.6%) had concomitant localized penile and scrotum swelling. He had severe disease activity since he was 7-year-old, manifested by diffuse cutaneous vasculitis, recurrent localized edema (limbs or face) and only one episode of generalized edema. At the age of 10, he presented edema of the genitalia associated with mild skin erythema. Penis, scrotum and testicular ultrasound as well as magnetic resonance imaging showed skin edema without testicular involvement. He was taking prednisone, methotrexate, cyclosporin, hydroxychloroquine and thalidomide. Improvement of skin rash, penile and scrotum swelling was noticed only with rituximab therapy. No adverse event was observed during anti-CD20 infusions and after six months of follow up. Penile and scrotum edema was a rare manifestation of ]DM which improved with anti-CD20 monoclonal antibody treatment.
- Subjects
DERMATOMYOSITIS; EDEMA; PENIS diseases; DISEASES; SCROTUM; PEDIATRICS; MONOCLONAL antibodies; MAGNETIC resonance imaging; VASCULITIS
- Publication
Acta Reumatológica Portuguesa, 2011, Vol 36, Issue 2, p176
- ISSN
0303-464X
- Publication type
Article