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- Title
Malignant monomorphic histiocytoma in children.
- Authors
Cozzutto, Cleto; Bronzini, Emilio; Bandelloni, Roberto; Guarino, Michele; De Bernardi, Bruno; Cozzutto, C; Bronzini, E; Bandelloni, R; Guarino, M; De Bernardi, B
- Abstract
Four cases of malignant histiocytoma in children are reported. Malignant histiocytoma is defined as a histologic variant of fibrohistiocytoma, characterized by a histologic absence of a fibroblastic component, and a predominant proliferation of malignant histiocytes with an epithelial-like appearance. However, the ultrastructural study of one case also revealed the presence of fibroblasts. Thus, an authentically pure form of malignant histiocytoma does not exist. Nonetheless, it is important to emphasize the histologic distinctions between malignant histiocytoma and malignant fibrohistiocytoma and to emphasize the possible differences in their biologic behavior.
- Publication
Cancer (0008543X), 1981, Vol 48, Issue 9, p2112
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19811101)48:9<2112::AID-CNCR2820480933>3.0.CO;2-W