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- Title
Looking Beyond the Lower Airways for Microbes Affecting Pulmonary Fibrosis.
- Authors
Darawshy, Fares; Molyneaux, Philip L.; Segal, Leopoldo N.
- Abstract
The article offers information on recent clinical trials using antibiotics to treat idiopathic pulmonary fibrosis (IPF) and their outcomes. Topics include the termination of the CleanUP-IPF trial and the EME-TIPAC study due to lack of efficacy in improving respiratory hospitalization or death rates, challenging the assumption of a causal link between lower airway bacterial burden and IPF progression.
- Subjects
IDIOPATHIC pulmonary fibrosis; INTERSTITIAL lung diseases
- Publication
American Journal of Respiratory & Critical Care Medicine, 2024, Vol 209, Issue 9, p1054
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202312-2255ED