Found: 34
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Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?
- Published in:
- 2005
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- Publication type:
- journal article
Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.
- Published in:
- 2003
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- Publication type:
- journal article
Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.
- Published in:
- 2003
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- Publication type:
- journal article
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41534-w
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- Publication type:
- Article
When one becomes many—Alternative splicing in β‐cell function and failure.
- Published in:
- Diabetes, Obesity & Metabolism, 2018, v. 20, p. 77, doi. 10.1111/dom.13388
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- Publication type:
- Article
Enhanced Signaling Downstream of Ribonucleic Acid-Activated Protein Kinase-Like Endoplasmic Reticulum Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 3, p. 1442, doi. 10.1210/jc.2009-2322
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- Publication type:
- Article
Mechanisms of Coxsackievirus-Induced Damage to Human Pancreatic β-Cells.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 1, p. 432, doi. 10.1210/jcem.85.1.6306
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- Publication type:
- Article
Mechanisms of Defective Glucose-Induced Insulin Release in Human Pancreatic Islets Transplanted to Diabetic Nude Mice.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 8, p. 2660, doi. 10.1210/jcem.82.8.4150
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- Publication type:
- Article
Reduced diabetogenic effect of streptozotocin in rats previously adapted to a high-protein, carbohydrate-free diet.
- Published in:
- 1984
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- Publication type:
- journal article
DNAJC3 deficiency induces β-cell mitochondrial apoptosis and causes syndromic young-onset diabetes.
- Published in:
- European Journal of Endocrinology, 2021, v. 184, n. 3, p. 459, doi. 10.1530/EJE-20-0636
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- Publication type:
- Article
The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells.
- Published in:
- Life Science Alliance, 2021, v. 4, n. 3, p. 1, doi. 10.26508/lsa.202000825
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- Publication type:
- Article
Genetic regulation of RNA splicing in human pancreatic islets.
- Published in:
- Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02757-0
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- Publication type:
- Article
Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes.
- Published in:
- Annals of Neurology, 2012, v. 72, n. 6, p. 971, doi. 10.1002/ana.23698
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- Publication type:
- Article
Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 8, p. 2274, doi. 10.1093/hmg/ddu745
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- Publication type:
- Article
Transcriptional Regulation of the Endoplasmic Reticulum Stress Gene Chop in Pancreatic Insulin-Producing Cells.
- Published in:
- Diabetes, 2007, v. 56, n. 4, p. 1069, doi. 10.2337/db06-1253
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- Publication type:
- Article
Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Disruption of the γ-Interferon Signaling Pathway at the Level of Signal Transducer and Activator of Transcription-1 Prevents Immune Destruction of β-cells.
- Published in:
- Diabetes, 2005, v. 54, n. 8, p. 2396, doi. 10.2337/diabetes.54.8.2396
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- Publication type:
- Article
Repair of Pancreatic β-Cells.
- Published in:
- Diabetes, 1993, v. 42, n. 10, p. 1383, doi. 10.2337/diab.42.10.1383
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- Publication type:
- Article
Genotoxic agents increase expression of growth arrest and DNA damage--inducible genes gadd 153 and gadd 45 in rat pancreatic islets.
- Published in:
- 1993
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- Publication type:
- journal article
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
- Published in:
- 1991
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- Publication type:
- journal article
Functional characteristics of rat pancreatic islets maintained in culture after exposure to human interleukin 1.
- Published in:
- 1988
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- Publication type:
- journal article
tRNA Methyltransferase Homolog Gene <i>TRMT10A</i> Mutation in Young Onset Diabetes and Primary Microcephaly in Humans.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003888
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- Publication type:
- Article
The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines.
- Published in:
- PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002552
- By:
- Publication type:
- Article
SRp55 Regulates a Splicing Network That Controls Human Pancreatic β-Cell Function and Survival.
- Published in:
- Diabetes, 2018, v. 67, n. 3, p. 423, doi. 10.2337/db17-0736
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- Publication type:
- Article
MicroRNAs miR-23a-3p, miR-23b-3p, and miR-149-5p Regulate the Expression of Proapoptotic BH3-Only Proteins DP5 and PUMA in Human Pancreatic β-Cells.
- Published in:
- 2017
- By:
- Publication type:
- journal article
A Missense Mutation in PPP1R15B Causes a Syndrome Including Diabetes, Short Stature, and Microcephaly.
- Published in:
- 2015
- By:
- Publication type:
- journal article
RNA Sequencing Identifies Dysregulation of the Human Pancreatic Islet Transcriptome by the Saturated Fatty Acid Palmitate.
- Published in:
- Diabetes, 2014, v. 63, n. 6, p. 1978, doi. 10.2337/db13-1383
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- Publication type:
- Article
Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress--Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis.
- Published in:
- Diabetes, 2012, v. 61, n. 11, p. 2763, doi. 10.2337/db12-0123
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- Publication type:
- Article
Heterozygous Inactivation of the Na/Ca Exchange Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass.
- Published in:
- Diabetes, 2011, v. 60, n. 8, p. 2076, doi. 10.2337/db10-0924
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- Publication type:
- Article
Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.
- Published in:
- 2009
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- Publication type:
- journal article
Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB.
- Published in:
- Diabetes, 2009, v. 58, n. 12, p. 2851, doi. 10.2337/db09-0685
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- Publication type:
- Article
PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.
- Published in:
- 2009
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- Publication type:
- journal article
PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-ϒ-Induced Pancreatic β-Cell Apoptosis.
- Published in:
- Diabetes, 2009, v. 58, n. 6, p. 1283, doi. 10.2337/db08-1510
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- Publication type:
- Article