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- Title
MRI findings in Pott's spine and correlating clinical progress with radiological findings.
- Authors
Misra, Usha Kant; Warrier, Siddharth; Kalita, Jayantee; Kumar, Sunil
- Abstract
Purpose: To document magnetic resonance imaging (MRI) changes in Pott's spine and to correlate these with clinical findings and outcome. Methods: Patients with Pott's spine having more than one set of MRI were included in the study. Patients were grouped according to timing of their second MRI. The MRI findings included changes in bone, disc, spinal cord, and soft tissue. The MRI changes were categorized into improvement, no change, or worsening. "Paradoxical worsening" was defined as radiological worsening in setting of clinical improvement, as described by improvement of Nurick's grade. Outcome was defined by mRS scale at three, six, and 12 months. The MRI findings and outcome were correlated. Results: The results are based on 36 patients. The MRI changes included vertebral changes in form of spondylodiscitis in 33 (92%), epidural abscess in 29 (81%), spinal cord changes including edema and granuloma in 17 (47%), paravertebral abscess in 29 (81%), and vertebral body collapse in 12 (33.3%) patients. At three months, clinical improvement occurred in eight out of 12 patients, deterioration in two, and no change in two. Spinal MRI revealed improvement in one patient only; whereas eight had deterioration and three had no change. At six months, all nine patients improved clinically, but MRI showed improvement in only four, while another four showed deterioration and one had no change. In the nine and 12 months group, while all patients clinically improved, MRI showed minimal worsening. Conclusion: In Pott's spine, the clinical improvement precedes the radiological improvement.
- Subjects
BONES; CONNECTIVE tissues; STATISTICAL correlation; INTERVERTEBRAL disk; MAGNETIC resonance imaging; EVALUATION of medical care; SPINAL cord; SPINAL tuberculosis; TIME; DISEASE progression; DESCRIPTIVE statistics; PROGNOSIS; RADIOGRAPHY
- Publication
Neuroradiology, 2020, Vol 62, Issue 7, p825
- ISSN
0028-3940
- Publication type
Article
- DOI
10.1007/s00234-020-02402-2