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- Title
Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008.
- Authors
Haiyang Yu; Wei Chen; Hongwei Chang; Renshu Tang; Jun Zhao; Lin Gan; Boyu Liu; Jason Chen; Mingli Wang
- Abstract
Enterovirus 71 (EV71) strains from children were characterized by full-length VP1 nucleotide sequencing. Out of 22 clinical specimens, five isolates identified as EV71 were recovered by virus isolation. The VP1 sequences of the five isolates had more than 97.4% sequence identity with prototype virus BrCr, clustering in the genotype A lineage. This represents the first record of genotype A EV71 in China since the BrCr prototype strain was discovered in the USA in 1969.
- Subjects
CHINA; ENTEROVIRUSES; HAND, foot &; mouth disease; PHYLOGENY; COXSACKIEVIRUS diseases
- Publication
Virus Genes, 2010, Vol 41, Issue 1, p1
- ISSN
0920-8569
- Publication type
Letter
- DOI
10.1007/s11262-010-0472-9