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- Title
Iron toxicity: relevance for dialysis patients.
- Authors
Fishbane, Steven; Mathew, Anna; Vaziri, Nosratola D.
- Abstract
Iron deficiency is common among patients with advanced kidney disease, particularly those requiring hemodialysis. Intravenous iron is a convenient treatment to supplement iron and is widely used among hemodialysis patients. Its efficacy is well established that, with treatment, hemoglobin levels rise and erythropoiesis-stimulating agent dose requirements are reduced. However, the safety of intravenous iron with respect to patient-centered outcomes has not been adequately studied. A variety of studies have indicated potential safety concerns, but most have been of small numbers of patients and with end points studied that have unclear clinical relevance. In this study, issues related to iron toxicity are reviewed.
- Subjects
TOXICOLOGY of iron; HEMODIALYSIS patients; HEMODIALYSIS; KIDNEY diseases; ERYTHROPOIESIS; DRUG dosage; PATIENT-centered care
- Publication
Nephrology Dialysis Transplantation, 2014, Vol 29, Issue 2, p255
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/gft269