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- Title
Mutagenic Effect during Combined Exposure to Ionizing and Non-Ionizing Electromagnetic Radiation.
- Authors
Styazhkina, E. V.; Akhmadullina, Yu. R.; Gainetdinova, Yu. V.; Payalova, E. A.; Pryakhin, E. A.
- Abstract
Using the method of dominant lethal mutations, we assessed the frequency of the death of Drosophila melanogaster embryos under combined exposure to ionizing γ-radiation and non-ionizing pulsed magnetic field at various doses and modes of exposure. Mutagenic effect of combined exposure is antagonistic in nature. The antagonism is more pronounced when the following mode of exposure was used: exposure to non-ionizing pulsed magnetic field for 5 h followed by exposure to γ-radiation at doses of 3, 10, and 60 Gy. In case of reverse sequence of exposures, the antagonistic effect was statistically significant after exposure to γ-radiation at doses of 3 and 10 Gy, whereas at a dose of 20 Gy, a synergistic interaction was noted.
- Subjects
NONIONIZING radiation; LETHAL mutations; MUTAGENS; ELECTROMAGNETIC radiation; DROSOPHILA melanogaster; EXPOSURE dose
- Publication
Bulletin of Experimental Biology & Medicine, 2024, Vol 176, Issue 5, p645
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-024-06085-0