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- Title
Chronic Kidney Disease—Mineral and Bone Disorder (CKD-MBD), from Bench to Bedside.
- Authors
Nitta, Kosaku; Hanafusa, Norio; Akiyama, Kenichi; Kawaguchi, Yuki; Tsuchiya, Ken
- Abstract
Chronic kidney disease—mineral and bone disorder (CKD-MBD) is a systemic disorder that increases the risk of morbidity and mortality in dialysis patients. CKD-MBD is highly prevalent in dialysis patients, and appropriate treatment is important for improving their outcomes. Inorganic phosphate, fibroblast growth factor 23, parathyroid hormone, and calciprotein particles are markers for critical components and effectors of CKD-MBD, and higher circulating levels of these markers are linked to cardiovascular diseases. In this short review, we focus on the pathogenesis and management of CKD-MBD in CKD patients, especially those on dialysis therapy, and discuss the prospects for improving the management in CKD patients, including those on dialysis.
- Subjects
TREATMENT of chronic kidney failure; CHRONIC kidney failure; BONE diseases; FIBROBLAST growth factors; BIOMARKERS; RENAL osteodystrophy; PARATHYROID hormone; HEMODIALYSIS; CALCIUM; COMORBIDITY; PHOSPHATES; DISEASE risk factors
- Publication
Kidney & Dialysis, 2023, Vol 3, Issue 1, p46
- ISSN
2673-8236
- Publication type
Article
- DOI
10.3390/kidneydial3010004