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- Title
EFFECTS OF THE ADMINISTRATION OF BREWED ROBUSTA COFFEE LEAVES ON TOTAL ANTIOXIDANT STATUS IN RATS WITH HIGH-FAT, HIGHFRUCTOSE DIET-INDUCED METABOLIC SYNDROME.
- Authors
Widyastuti, Nurmasari; Anjani, Gemala; Almira, Vita Gustin; Putri, Suci Eka; Pratiwi, Amali Rica
- Abstract
Robusta coffee (Coffea canephora) leaves contain phytochemical compounds and have antioxidant and anti-diabetic effects. This study investigated the effect of brewed Robusta coffee leaves on the total antioxidant status in metabolic syndrome rats. Metabolic syndrome in rats was induced by high-fat-fructose diet containing pork oil (20%), cholesterol (1.5%), cholic acid (0.5%), standard feed (80%), and fructose (1 mL per 200 g BW). The animals were categorized into normal control group (K1), metabolic syndrome control group without treatment (K2), mangiferin treatment group (X1), brewed Robusta coffee leaves 0.09 g per 200 BW group (X2), brewed Robusta coffee leaves 0.18 g per 200 BW group (X3), and brewed Robusta coffee leaves 0.36 g per 200 BW group (X4). Each dose of the coffee leaves was brewed with 3.6 mL of water at 70 °C for 10 min. The intervention was administered for 28 days. There was a significant increase in the total antioxidant status (p <0.000) in all the groups. In conclusion, the administration of brewed Robusta coffee leaves increased the total antioxidant status in metabolic syndrome rats.
- Subjects
COFFEE; PHYTOCHEMICALS; ANTIOXIDANTS; HYPOGLYCEMIC agents; METABOLIC syndrome; LABORATORY rats
- Publication
Slovak Journal of Food Sciences / Potravinarstvo, 2020, Vol 14, Issue 1, p258
- ISSN
1338-0230
- Publication type
Article
- DOI
10.5219/1350