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- Title
Elevated HbA1c levels in individuals not diagnosed with type 2 diabetes in Qatar: a pilot study.
- Authors
Mook-Kanamori, Marjonneke J.; El-Din Selim, Mohammed M.; Takiddin, Ahmed H.; Al-Mahmoud, Khoulood A.S.; Al-Homsi, Hala; McKeon, Cindy; Al Muftah, Wadha A.; Kader, Sara Abdul; Mook-Kanamori, Dennis O.; Suhre, Karsten
- Abstract
Background: The prevalence of type 2 diabetes (T2D) in Qatarand theMiddle East isone of the highest in theworld. It is estimated that about one quarter of the individuals with T2D are undiagnosed. Elevated HbA1c levels are an indicatorofT2Dora pre-diabetic state. In this studywe set out to examine which factors, such as anthropometric and socio-demographic risk factors, are associated with elevated HbA1c levels in a population without T2D. Methods: We examined 191 subjects with no record of T2D. Anthropometrics and HbA1c were measured. Socio-demographic (age, gender, ethnicity and educational level) and health information were assessed through questionnaires. Elevated HbA1c levels were defined as .6.0% (.42 mmol/mol). Individual risk factors were examined in relationship to having elevated HbA1c levels using logistic regression. Results: Thirty-eight (20%) study participants had elevated HbA1c levels. Participants from South Asian and Filipino descent were more likely to present with elevated HbA1c levels than Arab participants (adjusted odds ratios (OR): 13.30 (95% confidence interval (CI): 4.24, 41.79), p, 0.001 for South Asian and 4.54 (95% CI: 1.04, 19.83), p = 0.04 for Filipinos). A body mass index of above 30 kg/m2 was associated with elevated HbA1c levels (adjusted OR: 2.90 (95% CI: 1.29, 6.51), p = 0.01). Neither gender nor educational level was associated with elevated HbA1c levels. Conclusions: Elevated HbA1c levels in individuals not diagnosed with diabetes were most frequently found in the South Asian and Filipino immigrant population. Special attention should therefore be given to the early identification of T2D in these subjects.
- Subjects
QATAR; TYPE 2 diabetes diagnosis; HEMOGLOBINOMETRY; DISEASE prevalence; DEMOGRAPHIC characteristics; BODY mass index; PUBLIC health
- Publication
Qatar Medical Journal, 2014, Vol 2014, Issue 2, p1
- ISSN
0253-8253
- Publication type
Article
- DOI
10.5339/qmj.2014.17