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- Title
Long and Short of It: Early Response Predicts Longer-Term Outcomes in Pediatric Weight Management.
- Authors
Gross, Amy C.; Kaizer, Alexander M.; Kelly, Aaron S.; Rudser, Kyle D.; Ryder, Justin R.; Borzutzky, Claudia R.; Santos, Melissa; Tucker, Jared M.; Yee, Jennifer K.; Fox, Claudia K.; POWER Work Group
- Abstract
<bold>Objective: </bold>This study aimed to examine whether 1-month BMI improvement is predictive of superior 6- and 12-month BMI changes in a national sample of youth in pediatric weight management treatment.<bold>Methods: </bold>Participants were 4- to 18-year-olds from the Pediatric Obesity Weight Evaluation Registry, a prospective study collecting data from 31 pediatric weight management programs across the United States. Response at 1 month was defined as ≥ 3% BMI reduction; success at 6 and 12 months was defined as ≥ 5% BMI reduction from baseline. Analyses used linear and logistic regression with robust variance estimation.<bold>Results: </bold>Primary analyses were completed with 687 participants (mean age 12.2 years). One-month responders demonstrated significant improvements in BMI compared with nonresponders at 6 months (BMI, -2.05 vs. 0.05; %BMI, -5.81 vs. 0.23; P < 0.001 for all) and 12 months (BMI, -1.87 vs. 0.30; %BMI, -5.04 vs. 1.06; P < 0.001 for all). The odds of success for 1-month responders were 9.64 (95% CI: 5.85-15.87; P < 0.001) times that of nonresponders at 6 months and 5.24 (95% CI: 2.49-11.02; P < 0.001) times that of nonresponders at 12 months.<bold>Conclusions: </bold>In treatment-seeking youth with obesity, early BMI reduction was significantly associated with greater long-term BMI reduction. Nonresponders may benefit from early treatment redirection or intensification.
- Subjects
CHILDHOOD obesity; REGULATION of body weight; BODY mass index; METABOLIC disorders; WEIGHT gain
- Publication
Obesity (19307381), 2019, Vol 27, Issue 2, p272
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1002/oby.22367