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- Title
Evaluation of IL1β and IL6 Gingival Crevicular Fluid Levels during the Early Phase of Orthodontic Tooth Movement in Adolescents and Young Adults.
- Authors
Chelărescu, Simina; Șurlin, Petra; Decusară, Mioara; Oprică, Mădălina; Bud, Eugen; Teodorescu, Elina; Elsaafin, Mahmoud Nabil; Păcurar, Mariana
- Abstract
Background: The crevicular fluid analysis represents a useful diagnosis tool, with the help of which noninvasive cellular metabolic activity can be analyzed. The aim of the study is to investigate comparatively IL1β and IL6 in the gingival crevicular fluid of clinically healthy adolescents and young adults during the acute phase of orthodontic treatment. Methods: Gingival crevicular fluid was collected from 20 patients (aged between 11 and 28) undergoing orthodontic treatment. Measurements were taken before (T0) and after 24 h after distalization forces were activated (T1). IL1β and IL 6 were analyzed using Elisa tests. The statistical tests used were two-sided t tests. Results: Between the two time periods there was a significant raise both in the crevicular fluid rate (0.57 µL at T0 vs. 0.95 µL at T1, p = 0.001) and in IL1β levels (15.67 pg/µL at T0 vs. 27.94 pg/µL at T1, p = 0.009). We were able to identify IL6 only in a third of the sites. There is a significantly increased level of ILβ at T1 in adolescents, more than in young adults (42.96 pg/µL vs. 17.93 pg/µL, p = 0.006). Conclusions: In the early stage of orthodontic treatment, the periodontal tissues of adolescents are more responsive to orthodontic forces than those of young adults.
- Subjects
GINGIVAL fluid; CORRECTIVE orthodontics; YOUNG adults; INTERLEUKIN-6; GINGIVA; TEENAGERS; DIAGNOSIS
- Publication
Applied Sciences (2076-3417), 2021, Vol 11, Issue 2, p521
- ISSN
2076-3417
- Publication type
Article
- DOI
10.3390/app11020521