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- Title
Hypertrophic Lichenoid Eruption in a Child Successfully Treated Using Acitretin and Surgery: A Case Report and Literature Review.
- Authors
Geng, Songmei; Liu, Yanting; Wang, Hao; Yan, Huling; Niu, Xinwu; Toyohara, Jennifer P.; Xiao, Shengxiang
- Abstract
A 9-year-old boy presented with a history of keratotic violaceous plaques on the limbs and face for 8 years that had gradually progressed to erosive nodules on the extremities for 2 years. Several biopsies revealed hyperkeratosis, liquefactive degeneration of the basal layer, and a bandlike predominantly lymphocytic infiltrate. Based on the clinical and histologic findings, the patient was diagnosed with keratosis lichenoides chronica, a rare chronic dermatosis that is particularly uncommon in childhood. There are fewer than 20 reported cases of pediatric-onset keratosis lichenoides chronica in the current literature, with occurrence of pseudoepitheliomatous hyperplasia of primary keratosis lichenoides chronica lesions being even rarer. Here we present a unique pediatric-onset case accompanied by pseudoepitheliomatous hyperplasia that posed a significant treatment challenge to dermatologists. Significant improvement in the pseudoepitheliomatous skin lesions was achieved after treatment with oral acitretin capsules and surgical excision with skin grafting.
- Subjects
KERATOSIS; KERATINIZATION; HYPERPLASIA treatment; BLOOD cell count; IMMUNOASSAY; CELLULAR immunity
- Publication
Pediatric Dermatology, 2015, Vol 32, Issue 6, pe238
- ISSN
0736-8046
- Publication type
Article
- DOI
10.1111/pde.12658