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- Title
Giant condyloma of Buschke–Loewenstein in association with erythroderma.
- Authors
Antony, F. C.; Ardern-Jones, M.; Evans, A. V.; Rosenbaum, T.; Russell-Jones, R.
- Abstract
Summary The Buschke-Loewenstein tumour is regarded as a type of verrucous carcinoma occurring on anogenital mucosal surfaces. The tumour is locally invasive but displays a benign cytology and rarely metastasizes. It is associated with human papillomavirus types 6 and 11. We describe a case of Buschke-Loewenstein tumour occurring in a 61-year-old man which behaved in a locally aggressive manner and was associated with human papillomavirus type 16 and erythroderma which proved resistant to treatment. The patient refused surgery and therapy with interferon α was ineffective. Chemotherapy with systemic cisplatin and 5-fluorouracil produced a partial response before the patient succumbed from gram-negative septicaemia.
- Subjects
MUCOUS membrane cancer; PAPILLOMAVIRUSES
- Publication
Clinical & Experimental Dermatology, 2003, Vol 28, Issue 1, p46
- ISSN
0307-6938
- Publication type
Article
- DOI
10.1046/j.1365-2230.2003.01167.x