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- Title
Application of Patient-Specific Computational Fluid Dynamics in Coronary and Intra-Cardiac Flow Simulations: Challenges and Opportunities.
- Authors
Zhong, Liang; Zhang, Jun-Mei; Su, Boyang; Tan, Ru San; Allen, John C.; Kassab, Ghassan S.
- Abstract
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to the challenging field of virtual design and testing of technologies in a patient-specific environment. Given the recent advances in medical imaging, computational power and mathematical algorithms, patient-specific cardiac models can be produced from cardiac images faster, and more efficiently than ever before. The emergence of patient-specific computational fluid dynamics (CFD) has paved the way for the new field of computer-aided diagnostics. This article provides a review of CFD methods, challenges and opportunities in coronary and intra-cardiac flow simulations. It includes a review of market products and clinical trials. Key components of patient-specific CFD are covered briefly which include image segmentation, geometry reconstruction, mesh generation, fluid-structure interaction, and solver techniques.
- Subjects
COMPUTATIONAL fluid dynamics; DIAGNOSTIC imaging; MEDICAL imaging systems; CORONARY disease; MYOCARDIAL infarction
- Publication
Frontiers in Physiology, 2018, pN.PAG
- ISSN
1664-042X
- Publication type
Article
- DOI
10.3389/fphys.2018.00742