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Feasibility of Human Neural Stem Cell Transplantation for the Treatment of Acute Subdural Hematoma in a Rat Model: A Pilot Study.
Published in:
Frontiers in Neurology, 2019, p. N.PAG, doi. 10.3389/fneur.2019.00082
By:
- Yokobori, Shoji;
- Sasaki, Kazuma;
- Kanaya, Takahiro;
- Igarashi, Yutaka;
- Nakae, Ryuta;
- Onda, Hidetaka;
- Masuno, Tomohiko;
- Suda, Satoshi;
- Sowa, Kota;
- Nakajima, Masataka;
- Spurlock, Markus S.;
- Onn Chieng, Lee;
- Hazel, Tom G.;
- Johe, Karl;
- Gajavelli, Shyam;
- Fuse, Akira;
- Bullock, M. Ross;
- Yokota, Hiroyuki
Publication type:
Article
P2‐067: EFFECTS OF THE NEUROGENIC MOLECULE NSI‐189 ON INDICES OF COGNITION IN AN APP/TAU MOUSE MODEL OF ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P596, doi. 10.1016/j.jalz.2019.06.2474
By:
- Jolivalt, Corinne G.;
- Marquez, Alexandra;
- Guernsey, Lisa;
- Quach, David M.;
- Johe, Karl K.
Publication type:
Article
P2‐065: EFFECT OF NEUROGENIC COMPOUND NSI‐189 ON INDICES OF COGNITION AND ANXIETY IN A MOUSE MODEL (5XFAD) OF ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P691, doi. 10.1016/j.jalz.2018.06.750
By:
- Jolivalt, Corinne G.;
- Marquez, Alexandra;
- Quach, David M.;
- Johe, Karl K.
Publication type:
Article
Effects of Sertoli Cell-Conditioned Medium on Ventral Midbrain Neural Stem Cells: A Preliminary Report.
Published in:
Neurotoxicity Research, 2008, v. 13, n. 3/4, p. 241, doi. 10.1007/BF03033507
By:
- Shamekh, Rania;
- Saporta, Samuel;
- Cameron, Don F.;
- Willing, Alison E.;
- Sanberg, Cindy D.;
- Johe, Karl;
- Sanberg, P. R.
Publication type:
Article
Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient rats.
Published in:
Stem Cells Translational Medicine, 2020, v. 9, n. 2, p. 177, doi. 10.1002/sctm.19-0156
By:
- Marsala, Martin;
- Kamizato, Kota;
- Tadokoro, Takahiro;
- Navarro, Michael;
- Juhas, Stefan;
- Juhasova, Jana;
- Marsala, Silvia;
- Studenovska, Hana;
- Proks, Vladimir;
- Hazel, Tom;
- Johe, Karl;
- Kakinohana, Manabu;
- Driscoll, Shawn;
- Glenn, Thomas;
- Pfaff, Samuel;
- Ciacci, Joseph
Publication type:
Article
Stable Intracerebral Transplantation of Neural Stem Cells for the Treatment of Paralysis Due to Ischemic Stroke.
Published in:
Stem Cells Translational Medicine, 2019, v. 8, n. 10, p. 999, doi. 10.1002/sctm.18-0220
By:
- Zhang, Guangzhu;
- Li, Ying;
- Reuss, James L.;
- Liu, Nan;
- Wu, Cuiying;
- Li, Jingpo;
- Xu, Shuangshuang;
- Wang, Feng;
- Hazel, Thomas G.;
- Cunningham, Miles;
- Zhang, Hongtian;
- Dai, Yiwu;
- Hong, Peng;
- Zhang, Ping;
- He, Jianghong;
- Feng, Huiru;
- Lu, Xiangdong;
- Ulmer, John L.;
- Johe, Karl K.;
- Xu, Ruxiang
Publication type:
Article
Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation.
Published in:
Stem Cell Research & Therapy, 2013, v. 4, n. 3, p. 1, doi. 10.1186/scrt209
By:
- van Gorp, Sebastiaan;
- Leerink, Marjolein;
- Kakinohana, Osamu;
- Platoshyn, Oleksandr;
- Santucci, Camila;
- Galik, Jan;
- Joosten, Elbert A.;
- Hruska-Plochan, Marian;
- Goldberg, Danielle;
- Marsala, Silvia;
- Johe, Karl;
- Ciacci, Joseph D.;
- Marsala, Martin
Publication type:
Article
Autocrine Production of IGF-I Increases Stem Cell-Mediated Neuroprotection.
Published in:
Stem Cells, 2015, v. 33, n. 5, p. 1480, doi. 10.1002/stem.1933
By:
- Lunn, J. Simon;
- Sakowski, Stacey A.;
- McGinley, Lisa M.;
- Pacut, Crystal;
- Hazel, Thomas G.;
- Johe, Karl;
- Feldman, Eva L.
Publication type:
Article
Lumbar Intraspinal Injection of Neural Stem Cells in Patients with Amyotrophic Lateral Sclerosis: Results of a Phase I Trial in 12 Patients.
Published in:
Stem Cells, 2012, v. 30, n. 6, p. 1144, doi. 10.1002/stem.1079
By:
- Glass, Jonathan D.;
- Boulis, Nicholas M.;
- Johe, Karl;
- Rutkove, Seward B.;
- Federici, Thais;
- Polak, Meraida;
- Kelly, Crystal;
- Feldman, Eva L.
Publication type:
Article
Combined Immunosuppressive Agents or CD4 Antibodies Prolong Survival of Human Neural Stem Cell Grafts and Improve Disease Outcomes in Amyotrophic Lateral Sclerosis Transgenic Mice.
Published in:
Stem Cells, 2006, v. 24, n. 8, p. 1976, doi. 10.1634/stemcells.2005-0518
By:
- Jun Yan;
- Leyan Xu;
- Welsh, Annie M.;
- Chen, David;
- Hazel, Thomas;
- Johe, Karl;
- Koliatsosa, Vassilis E.
Publication type:
Article
Behavioral and Histopathological Assessment of Adult Ischemic Rat Brains after Intracerebral Transplantation of NSI-566RSC Cell Lines.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091408
By:
- Tajiri, Naoki;
- Quach, David M.;
- Kaneko, Yuji;
- Wu, Stephanie;
- Lee, David;
- Lam, Tina;
- Hayama, Ken L.;
- Hazel, Thomas G.;
- Johe, Karl;
- Wu, Michael C.;
- Borlongan, Cesar V.
Publication type:
Article
Human Neural Stem Cell Replacement Therapy for Amyotrophic Lateral Sclerosis by Spinal Transplantation.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042614
By:
- Hefferan, Michael P.;
- Galik, Jan;
- Kakinohana, Osamu;
- Sekerkova, Gabriela;
- Santucci, Camila;
- Marsala, Silvia;
- Navarro, Roman;
- Hruska-Plochan, Marian;
- Johe, Karl;
- Feldman, Eva;
- Cleveland, Don W.;
- Marsala, Martin;
- Kincaid, Anthony E.
Publication type:
Article
Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease.
Published in:
Stem Cells Translational Medicine, 2016, v. 5, n. 3, p. 379, doi. 10.5966/sctm.2015-0103
By:
- McGinley, Lisa M.;
- Sims, Erika;
- Lunn, J. Simon;
- Kashlan, Osama N.;
- Chen, Kevin S.;
- Bruno, Elizabeth S.;
- Pacut, Crystal M.;
- Hazel, Tom;
- Johe, Karl;
- Sakowski, Stacey A.;
- Feldman, Eva L.
Publication type:
Article
Long‐term Phase 1/2 intraspinal stem cell transplantation outcomes in ALS.
Published in:
Annals of Clinical & Translational Neurology, 2018, v. 5, n. 6, p. 730, doi. 10.1002/acn3.567
By:
- Goutman, Stephen A.;
- Brown, Morton B.;
- Glass, Jonathan D.;
- Boulis, Nicholas M.;
- Johe, Karl;
- Hazel, Tom;
- Cudkowicz, Merit;
- Atassi, Nazem;
- Borges, Lawrence;
- Patil, Parag G.;
- Sakowski, Stacey A.;
- Feldman, Eva L.
Publication type:
Article
Human neural stem cell transplantation into the corpus callosum of Alzheimer's mice.
Published in:
Annals of Clinical & Translational Neurology, 2017, v. 4, n. 10, p. 749, doi. 10.1002/acn3.443
By:
- McGinley, Lisa M.;
- Kashlan, Osama N.;
- Chen, Kevin S.;
- Bruno, Elizabeth S.;
- Hayes, John M.;
- Backus, Carey;
- Feldman, Seth;
- Kashlan, Bader N.;
- Johe, Karl;
- Feldman, Eva L.
Publication type:
Article
Pig models of neurodegenerative disorders: Utilization in cell replacement-based preclinical safety and efficacy studies.
Published in:
Journal of Comparative Neurology, 2014, v. 522, n. 12, p. 2784, doi. 10.1002/cne.23575
By:
- Dolezalova, Dasa;
- Hruska‐Plochan, Marian;
- Bjarkam, Carsten R.;
- Sørensen, Jens Christian H.;
- Cunningham, Miles;
- Weingarten, David;
- Ciacci, Joseph D.;
- Juhas, Stefan;
- Juhasova, Jana;
- Motlik, Jan;
- Hefferan, Michael P.;
- Hazel, Tom;
- Johe, Karl;
- Carromeu, Cassiano;
- Muotri, Alysson;
- Bui, Jack;
- Strnadel, Jan;
- Marsala, Martin
Publication type:
Article
Intraspinal neural stem cell transplantation in amyotrophic lateral sclerosis: Phase 1 trial outcomes.
Published in:
Annals of Neurology, 2014, v. 75, n. 3, p. 363, doi. 10.1002/ana.24113
By:
- Feldman, Eva L.;
- Boulis, Nicholas M.;
- Hur, Junguk;
- Johe, Karl;
- Rutkove, Seward B.;
- Federici, Thais;
- Polak, Meraida;
- Bordeau, Jane;
- Sakowski, Stacey A.;
- Glass, Jonathan D.
Publication type:
Article
Remediation of Radiation-Induced Cognitive Dysfunction through Oral Administration of the Neuroprotective Compound NSI-189.
Published in:
Radiation Research, 2018, v. 189, n. 4, p. 345, doi. 10.1667/RR14879.1
By:
- Allen, Barrett D.;
- Acharya, Munjal M.;
- Lu, Celine;
- Giedzinski, Erich;
- Chmielewski, Nicole N.;
- Quach, David;
- Hefferan, Mike;
- Johe, Karl K.;
- Limoli, Charles L.
Publication type:
Article
NSI-189, a small molecule with neurogenic properties, exerts behavioral, and neurostructural benefits in stroke rats.
Published in:
Journal of Cellular Physiology, 2017, v. 232, n. 10, p. 2731, doi. 10.1002/jcp.25847
By:
- Tajiri, Naoki;
- Quach, David M.;
- Kaneko, Yuji;
- Wu, Stephanie;
- Lee, David;
- Lam, Tina;
- Hayama, Ken L.;
- Hazel, Thomas G.;
- Johe, Karl;
- Wu, Michael C.;
- Borlongan, Cesar V.
Publication type:
Article
Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33017-6
By:
- McGinley, Lisa M.;
- Kashlan, Osama N.;
- Bruno, Elizabeth S.;
- Chen, Kevin S.;
- Hayes, John M.;
- Kashlan, Samy R.;
- Raykin, Julia;
- Johe, Karl;
- Murphy, Geoffrey G.;
- Feldman, Eva L.
Publication type:
Article
Characterization of a human fetal spinal cord stem cell line, NSI-566RSC, and its induction to functional motoneurons.
Published in:
Journal of Tissue Engineering & Regenerative Medicine, 2010, v. 4, n. 3, p. 181, doi. 10.1002/term.223
By:
- Guo, Xiufang;
- Johe, Karl;
- Molnar, Peter;
- Davis, Hedvika;
- Hickman, James
Publication type:
Article
Targeted intraspinal injections to assess therapies in rodent models of neurological disorders.
Published in:
Nature Protocols, 2019, v. 14, n. 2, p. 331, doi. 10.1038/s41596-018-0095-5
By:
- Chen, Kevin S.;
- McGinley, Lisa M.;
- Kashlan, Osama N.;
- Hayes, John M.;
- Bruno, Elizabeth S.;
- Chang, Josh S.;
- Mendelson, Faye E.;
- Tabbey, Maegan A.;
- Johe, Karl;
- Sakowski, Stacey A.;
- Feldman, Eva L.
Publication type:
Article
Extensive Neuronal Differentiation of Human Neural Stem Cell Grafts in Adult Rat Spinal Cord.
Published in:
PLoS Medicine, 2007, v. 4, n. 2, p. 318, doi. 10.1371/journal.pmed.0040039
By:
- Yan, Jun;
- Leyan Xu;
- Welsh, Annie M.;
- Hatfield, Glen;
- Hazel, Thomas;
- Johe, Karl;
- Koliatsos, Vassilis E.
Publication type:
Article
Analysis of graft survival in a trial of stem cell transplant in ALS.
Published in:
Annals of Clinical & Translational Neurology, 2014, v. 1, n. 11, p. 900, doi. 10.1002/acn3.134
By:
- Tadesse, Tezeta;
- Gearing, Marla;
- Senitzer, David;
- Saxe, Debra;
- Brat, Daniel J.;
- Bray, Robert;
- Gebel, Howard;
- Hill, Charles;
- Boulis, Nicholas;
- Riley, Jonathan;
- Feldman, Eva;
- Johe, Karl;
- Hazel, Thomas;
- Polak, Meraida;
- Bordeau, Jane;
- Federici, Thais;
- Glass, Jonathan D.
Publication type:
Article
An immune deficient mouse model for mucopolysaccharidosis IIIA (Sanfilippo syndrome).
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45178-0
By:
- Pollock, Kari;
- Noritake, Sabrina;
- Imai, Denise M.;
- Pastenkos, Gabrielle;
- Olson, Marykate;
- Cary, Whitney;
- Yang, Sheng;
- Fierro, Fernando A.;
- White, Jeannine;
- Graham, Justin;
- Dahlenburg, Heather;
- Johe, Karl;
- Nolta, Jan A.
Publication type:
Article
Amelioration of Both Central and Peripheral Neuropathy in Mouse Models of Type 1 and Type 2 Diabetes by the Neurogenic Molecule NSI-189.
Published in:
2019
By:
- Jolivalt, Corinne G.;
- Marquez, Alexandra;
- Quach, David;
- Navarro Diaz, Michelle C.;
- Anaya, Carlos;
- Kifle, Betelhem;
- Muttalib, Nabeel;
- Sanchez, Gabriela;
- Guernsey, Lucy;
- Hefferan, Mike;
- Smith, Darrel R.;
- Fernyhough, Paul;
- Johe, Karl;
- Calcutt, Nigel A.
Publication type:
journal article

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