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- Title
Effects of dietary supplementation of lead (Pb) on biochemical, gross and histo-morphological changes in different organs of broiler chicken.
- Authors
Monjur, T.; Rahaman, T.; Islam, M. S.; Ferdous, K. A.
- Abstract
Background Nowadays poultry industry, an important sector is becoming a serious threat to public health due to the heavy metal exposure & accumulation in poultry tissues. Therefore, our recent study was aimed to investigate the toxic effects of lead (Pb) exposure in broiler chicken. Methods A total number of 72 broiler chicks (Cobb-500, 12th day old) were assigned to four dietary treatments with three replicates. Control group received only basal diet without any supplementation. The other groups T1, T2 and T3 received feed with supplemented Pb @ 10, 30 and 50mg/kg feed, respectively. The body weight of each bird was weighed at 3 days interval. Results Lead caused elevation of SGPT/ALT (P<0.01) and decreased serum creatinine attributed to pathological lesions including enlarged, pale & friable liver, swollen kidneys and splenomegaly in experimental groups. On histopathological examination, liver shows cirrhosis and necrosis in all treated groups. In the kidney, glomerulus was filled with reactive cells in group T1 while fibrosis and necrosis were found in groups T2 & T3. Conclusions Lead toxicity in broiler had a dose-dependent effect on body weight gain, blood parameters, gross and histological changes.
- Subjects
BROILER chickens; DIETARY supplements; CIRRHOSIS of the liver; WEIGHT gain; BODY weight
- Publication
Bangladesh Journal of Veterinary Medicine, 2018, Vol 16, Issue 2, p137
- ISSN
1729-7893
- Publication type
Article
- DOI
10.33109/bjvmjd1802