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Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13185, doi. 10.3390/ijms222413185
By:
- Dedic, Nina;
- Dworak, Heather;
- Zeni, Courtney;
- Rutigliano, Grazia;
- Howes, Oliver D.
Publication type:
Article
Effect of TAAR1/5-HT1A agonist SEP-363856 on REM sleep in humans.
Published in:
Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01331-9
By:
- Hopkins, Seth C.;
- Dedic, Nina;
- Koblan, Kenneth S.
Publication type:
Article
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT<sub>1A</sub> Receptor Agonist for the Treatment of Schizophrenia.
Published in:
Pharmaceutical Research, 2022, v. 39, n. 5, p. 837, doi. 10.1007/s11095-022-03267-1
By:
- Xiao, Guangqing;
- Chen, Yu-Luan;
- Dedic, Nina;
- Xie, Linghong;
- Koblan, Kenneth S.;
- Galluppi, Gerald R.
Publication type:
Article
TAAR1 agonist ulotaront delays gastric emptying of solids in patients with schizophrenia and concurrent metabolic syndrome with prediabetes.
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 6, p. 2466, doi. 10.1111/dom.15569
By:
- Milanović, Snežana;
- Dedic, Nina;
- Lew, Robert;
- Burton, Duane;
- Koblan, Kenneth S.;
- Camilleri, Michael;
- Hopkins, Seth C.
Publication type:
Article
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46953-x
By:
- Hartmann, Jakob;
- Bajaj, Thomas;
- Otten, Joy;
- Klengel, Claudia;
- Ebert, Tim;
- Gellner, Anne-Kathrin;
- Junglas, Ellen;
- Hafner, Kathrin;
- Anderzhanova, Elmira A.;
- Tang, Fiona;
- Missig, Galen;
- Rexrode, Lindsay;
- Trussell, Daniel T.;
- Li, Katelyn X.;
- Pöhlmann, Max L.;
- Mackert, Sarah;
- Geiger, Thomas M.;
- Heinz, Daniel E.;
- Lardenoije, Roy;
- Dedic, Nina
Publication type:
Article
Ulotaront: review of preliminary evidence for the efficacy and safety of a TAAR1 agonist in schizophrenia.
Published in:
European Archives of Psychiatry & Clinical Neuroscience, 2023, v. 273, n. 7, p. 1543, doi. 10.1007/s00406-023-01580-3
By:
- Achtyes, Eric D.;
- Hopkins, Seth C.;
- Dedic, Nina;
- Dworak, Heather;
- Zeni, Courtney;
- Koblan, Kenneth
Publication type:
Article
Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.
Published in:
Frontiers in Cellular Neuroscience, 2013, v. 7, p. 1, doi. 10.3389/fncel.2013.00091
By:
- Kratzer, Stephan;
- Mattusch, Corinna;
- Metzger, Michael W.;
- Dedic, Nina;
- Noll-Hussong, Michael;
- Kafitz, Karl W.;
- Eder, Matthias;
- Deussing, Jan M.;
- Holsboer, Florian;
- Kochs, Eberhard;
- Rammes, Gerhard
Publication type:
Article
Assessing Behavioural Effects of Chronic HPA Axis Activation Using Conditional CRH-Overexpressing Mice.
Published in:
Cellular & Molecular Neurobiology, 2012, v. 32, n. 5, p. 815, doi. 10.1007/s10571-011-9784-0
By:
- Dedic, Nina;
- Touma, Chadi;
- Romanowski, Cristoph;
- Schieven, Marcel;
- Kühne, Claudia;
- Ableitner, Martin;
- Lu, Ailing;
- Holsboer, Florian;
- Wurst, Wolfgang;
- Kimura, Mayumi;
- Deussing, Jan
Publication type:
Article
Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition.
Published in:
Nature Neuroscience, 2015, v. 18, n. 2, p. 239, doi. 10.1038/nn.3912
By:
- Vogl, Annette M;
- Brockmann, Marisa M;
- Giusti, Sebastian A;
- Maccarrone, Giuseppina;
- Vercelli, Claudia A;
- Bauder, Corinna A;
- Richter, Julia S;
- Roselli, Francesco;
- Hafner, Anne-Sophie;
- Dedic, Nina;
- Wotjak, Carsten T;
- Vogt-Weisenhorn, Daniela M;
- Choquet, Daniel;
- Turck, Christoph W;
- Stein, Valentin;
- Deussing, Jan M;
- Refojo, Damian
Publication type:
Article
Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality.
Published in:
Journal of Neuroscience, 2017, v. 37, n. 48, p. 11688, doi. 10.1523/JNEUROSCI.3487-16.2017
By:
- Metzger, Michael W.;
- Walser, Sandra M.;
- Dedic, Nina;
- Aprile-Garcia, Fernando;
- Jakubcakova, Vladimira;
- Adamczyk, Marek;
- Webb, Katharine J.;
- Uhr, Manfred;
- Refojo, Damian;
- Schmidt, Mathias V.;
- Friess, Elisabeth;
- Steiger, Axel;
- Kimura, Mayumi;
- Alon Chen;
- Holsboer, Florian;
- Arzt, Eduardo;
- Wurst, Wolfgang;
- Deussing, Jan M.
Publication type:
Article
Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans.
Published in:
PLoS Medicine, 2014, v. 11, n. 11, p. 1, doi. 10.1371/journal.pmed.1001755
By:
- Gassen, Nils C.;
- Hartmann, Jakob;
- Zschocke, Jürgen;
- Stepan, Jens;
- Hafner, Kathrin;
- Zellner, Andreas;
- Kirmeier, Thomas;
- Kollmannsberger, Lorenz;
- Wagner, Klaus V.;
- Dedic, Nina;
- Balsevich, Georgia;
- Deussing, Jan M.;
- Kloiber, Stefan;
- Lucae, Susanne;
- Holsboer, Florian;
- Eder, Matthias;
- Uhr, Manfred;
- Ising, Marcus;
- Schmidt, Mathias V.;
- Rein, Theo
Publication type:
Article
Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties.
Published in:
Journal of Neuroscience, 2015, v. 35, n. 24, p. 9007, doi. 10.1523/JNEUROSCI.4024-14.2015
By:
- Hartmann, Jakob;
- Wagner, Klaus V.;
- Gaali, Steffen;
- Kirschner, Alexander;
- Kozany, Christian;
- Rühter, Gerd;
- Dedic, Nina;
- Häusl, Alexander S.;
- Hoeijmakers, Lianne;
- Westerholz, Sören;
- Namendorf, Christian;
- Gerlach, Tamara;
- Uhr, Manfred;
- Chen, Alon;
- Deussing, Jan M.;
- Holsboer, Florian;
- Hausch, Felix;
- Schmidt, Mathias V.
Publication type:
Article

Found: 12