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Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine‐Releasing Capacity.
Published in:
Stem Cells Translational Medicine, 2018, v. 7, n. 6, p. 477, doi. 10.1002/sctm.16-0272
By:
- Poppe, Daniel;
- Doerr, Jonas;
- Schneider, Marion;
- Wilkens, Ruven;
- Steinbeck, Julius A.;
- Ladewig, Julia;
- Tam, Allison;
- Paschon, David E.;
- Gregory, Philip D.;
- Reik, Andreas;
- Müller, Christa E.;
- Koch, Philipp;
- Brüstle, Oliver
Publication type:
Article
Controlling long-range genomic interactions to reprogram the β-globin locus.
Published in:
2013
By:
- Deng, Wulan;
- Rupon, Jeremy W.;
- Hongxin Wang;
- Reik, Andreas;
- Gregory, Philip D.;
- Blobel, Gerd A.
Publication type:
Conference Paper
Genome editing with engineered zinc finger nucleases.
Published in:
2010
By:
- Urnov, Fyodor D.;
- Rebar, Edward J.;
- Holmes, Michael C.;
- Zhang, H. Steve;
- Gregory, Philip D.
Publication type:
journal article
Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
Published in:
Molecular Therapy, 2015, v. 23, n. 8, p. 1380, doi. 10.1038/mt.2015.71
By:
- Beane, Joal D;
- Lee, Gary;
- Zheng, Zhili;
- Mendel, Matthew;
- Abate-Daga, Daniel;
- Bharathan, Mini;
- Black, Mary;
- Gandhi, Nimisha;
- Yu, Zhiya;
- Chandran, Smita;
- Giedlin, Martin;
- Ando, Dale;
- Miller, Jeff;
- Paschon, David;
- Guschin, Dmitry;
- Rebar, Edward J;
- Reik, Andreas;
- Holmes, Michael C;
- Gregory, Philip D;
- Restifo, Nicholas P
Publication type:
Article
Genomic Editing of the HIV-1 Coreceptor CCR5 in Adult Hematopoietic Stem and Progenitor Cells Using Zinc Finger Nucleases.
Published in:
Molecular Therapy, 2013, v. 21, n. 6, p. 1259, doi. 10.1038/mt.2013.65
By:
- Li, Lijing;
- Krymskaya, Ludmila;
- Wang, Jianbin;
- Henley, Jill;
- Rao, Anitha;
- Cao, Lan-Feng;
- Tran, Chy-Anh;
- Torres-Coronado, Monica;
- Gardner, Agnes;
- Gonzalez, Nancy;
- Kim, Kenneth;
- Liu, Pei-Qi;
- Hofer, Ursula;
- Lopez, Evan;
- Gregory, Philip D;
- Liu, Qing;
- Holmes, Michael C;
- Cannon, Paula M;
- Zaia, John A;
- DiGiusto, David L
Publication type:
Article
A Designed Zinc-finger Transcriptional Repressor of Phospholamban Improves Function of the Failing Heart.
Published in:
Molecular Therapy, 2012, v. 20, n. 8, p. 1508, doi. 10.1038/mt.2012.80
By:
- Zhang, H Steve;
- Liu, Dingang;
- Huang, Yan;
- Schmidt, Stefan;
- Hickey, Reed;
- Guschin, Dmitry;
- Su, Haili;
- Jovin, Ion S;
- Kunis, Mike;
- Hinkley, Sarah;
- Liang, Yuxin;
- Hinh, Linda;
- Spratt, S Kaye;
- Case, Casey C;
- Rebar, Edward J;
- Ehrlich, Barbara;
- Gregory, Philip D;
- Giordano, Frank J
Publication type:
Article
Zinc-finger Nuclease Editing of Human cxcr4 Promotes HIV-1 CD4+ T Cell Resistance and Enrichment.
Published in:
2012
By:
- Yuan, Jinyun;
- Wang, Jianbin;
- Crain, Karen;
- Fearns, Colleen;
- Kim, Kenneth A;
- Hua, Kevin L;
- Gregory, Philip D;
- Holmes, Michael C;
- Torbett, Bruce E
Publication type:
Art Reproduction
Gene Transfer of An Engineered Zinc Finger Protein Enhances the Anti-angiogenic Defense System.
Published in:
Molecular Therapy, 2007, v. 15, n. 11, p. 1917, doi. 10.1038/sj.mt.6300280
By:
- Yokoi, Katsutoshi;
- Zhang, Huanda Steve;
- Shu Kachi;
- Balaggan, Kamaljit S.;
- Qi Yu;
- Guschin, Dmitry;
- Kunis, Mike;
- Surosky, Richard;
- Africa, Liza M.;
- Bainbridge, James W.;
- Spratt, Sharon Kaye;
- Gregory, Philip D.;
- Ali, Robin R.;
- Campochiaro, Peter A.
Publication type:
Article
1003. Targeted Site-Specific Integration in Human Cells Using Designed Zinc Finger Nucleases.
Published in:
Molecular Therapy, 2006, v. 13, p. S386, doi. 10.1016/j.ymthe.2006.08.1097
By:
- Urnov, Fyodor D.;
- Lombardo, Angelo;
- Rock, Jeremy;
- Moehle, Erica;
- Miller, Jeffrey C.;
- Ya-Li Lee;
- Gregory, Philip D.;
- Naldini, Luigi;
- Holmes, Michael C.
Publication type:
Article
1010. Developing a Potential Pain Therapy Using Engineered Zinc Finger Protein Repressors of the Sodium Channel PN3.
Published in:
Molecular Therapy, 2006, v. 13, p. S389, doi. 10.1016/j.ymthe.2006.08.1104
By:
- Tan, Siyuan;
- Doroudchi, Mohammad M.;
- Zhong, Xiaohong;
- Qiao, Julie;
- Zhang, Steve;
- Gregory, Philip D.
Publication type:
Article
1040. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome Using Designed Zinc Finger Endonucleases.
Published in:
Molecular Therapy, 2006, v. 13, p. S398, doi. 10.1016/j.ymthe.2006.08.1136
By:
- Davis, Brian R.;
- Prokopishyn, Nicole L.;
- Rosenberg, Jonathan;
- DiCola, Michael;
- Brosius, Jennifer;
- Michael Blaese, R.;
- Metz, Richard A.;
- Zhang, Lei;
- Xia, Danny;
- Miller, Jeffrey C.;
- Kim, Kenneth;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article
555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene.
Published in:
Molecular Therapy, 2006, v. 13, p. S214, doi. 10.1016/j.ymthe.2006.08.627
By:
- Holmes, Michael C.;
- Liu, Linda;
- Perez, Elena;
- Linhong Li;
- Shivakumar, Rama;
- Allen, Cornell;
- Olga Liu;
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Kim, Kenneth;
- Rebar, Edward J.;
- Ando, Dale;
- Gregory, Philip D.;
- Riley, James;
- Peshwa, Madhusudan;
- June, Carl
Publication type:
Article
738. Towards Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integrase Defective Lentiviral Delivery*.
Published in:
Molecular Therapy, 2006, v. 13, p. S285, doi. 10.1016/j.ymthe.2006.08.819
By:
- Lombardo, Angelo;
- Beausejour, Christian;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Aiuti, Alessandro;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Naldini, Luigi
Publication type:
Article
758. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs).
Published in:
Molecular Therapy, 2006, v. 13, p. S293, doi. 10.1016/j.ymthe.2006.08.842
By:
- Perez, Elena;
- Jouvenot, Yann;
- Miller, Jeffrey C.;
- Olga Liu;
- Jianbin Wang;
- Guschin, Dmitry;
- Bartsevich, Victor;
- Kim, Kenneth;
- Ya-Li Lee;
- Rebar, Edward J.;
- Ando, Dale;
- Gregory, Philip D.;
- Riley, James;
- Holmes, Michael C.;
- June, Carl
Publication type:
Article
788. Engineered Zinc Finger Protein Transcription Factors as a Potential Therapy for Choroidal Neovascularization.
Published in:
Molecular Therapy, 2006, v. 13, p. S305, doi. 10.1016/j.ymthe.2006.08.876
By:
- Steve Zhang;
- Kachi, Shu;
- Hackett, Sean F.;
- Kachi, Michido;
- Akiyama, Hideo;
- Umeda, Naoyasu;
- Yokoi, Katsutoshi;
- Pei-qi Liu;
- Veres, Gabor;
- Gregory, Philip D.;
- Campochiaro, Peter A.
Publication type:
Article
1072. Superactivation of the SRα and CMV Promoters Using Designed Zinc Finger Proteins
Published in:
2005
By:
- Bartsevich, Victor V.;
- Reik, Andreas;
- Zhou, Yuanyue;
- Kong, Michelle;
- Li, Xiao-Yong;
- Warfe, Lyndon;
- Zhang, Lei;
- Case, Casey C.;
- Collingwood, Trevor;
- Gregory, Philip D.;
- Rebar, Edward J.
Publication type:
Abstract
974. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs)
Published in:
2005
By:
- Jouvenot, Yann;
- Perez, Elena;
- Urnov, Fyodor D.;
- Beausejour, Christian;
- Rock, Jeremy;
- Lee, Ya-Li;
- Miller, Jeffrey C.;
- Rebar, Edward J.;
- Holmes, Michael C.;
- Ando, Dale;
- Riley, Jim;
- Gregory, Philip D.;
- June, Carl
Publication type:
Abstract
646. Zinc Finger Protein Transcription Factors as Potential Therapeutic Agents for the Treatment of Neuropathic Pain
Published in:
2005
By:
- Tan, Siyuan;
- McNamara, Andrew;
- Jouvenot, Yann;
- Krisky, Dave;
- Wolfe, Darren;
- Compos, Bradley;
- Zhong, Xiaohong;
- Glorioso, Joe;
- Zhang, H. Steven;
- Gregory, Philip D.
Publication type:
Abstract
379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification Therapies
Published in:
2005
By:
- Miller, Jeffrey C.;
- Zhang, Lei;
- Urnov, Fyodor D.;
- Patterson, Sarah;
- Xia, Danny;
- Rock, Jeremy;
- Augustus, Sheldon;
- Pabo, Carl O.;
- Gregory, Philip D.;
- Rebar, Edward J.;
- Holmes, Michael C.
Publication type:
Abstract
346. Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integration Defective Lentiviral Delivery
Published in:
2005
By:
- Lombardo, Angelo;
- Beausejour, Christian;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Holmes, Michael C.;
- Gregory, Philip D.;
- Naldini, Luigi
Publication type:
Abstract
337. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome with Engineered Zinc Finger Nucleases
Published in:
2005
By:
- Zhang, Lei;
- Urnov, Fyodor D.;
- Miller, Jeffrey C.;
- Beausejour, Christian;
- Lee, Ya-Li;
- Rock, Jeremy;
- Kim, Kenneth;
- Holmes, Michael C.;
- Gregory, Philip D.
Publication type:
Abstract
85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell Anemia
Published in:
2005
By:
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Lee, Ya-li;
- Rock, Jeremy;
- Sorba, Tyler;
- Patterson, Sarah;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Rebar, Edward J.
Publication type:
Abstract
43. Targeting the Biology of Heart Disease: Engineered Zinc Finger Protein Repressors of Phospholamban as a Potential Therapy for Congestive Heart Failure
Published in:
2005
By:
- Zhang, H. Steve;
- Zhang, Lei;
- Huang, Yan;
- Liu, Dinggang;
- Liang, Yuxin;
- Hickey, Reed;
- Guschin, Dmitry;
- Chandler, Simon;
- Kunis, Mike;
- Hinh, Linda;
- Xia, Danny;
- Zhong, Xiaohong;
- Spratt, S. Kaye;
- Martin, J. Tyler;
- Case, Casey C.;
- Ando, Dale;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Giordano, Frank
Publication type:
Abstract
Activation domains for controlling plant gene expression using designed transcription factors.
Published in:
Plant Biotechnology Journal, 2013, v. 11, n. 6, p. 671, doi. 10.1111/pbi.12057
By:
- Li, Jianquan;
- Blue, Ryan;
- Zeitler, Bryan;
- Strange, Tonya L.;
- Pearl, Jocelynn R.;
- Huizinga, David H.;
- Evans, Steve;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Petolino, Joseph F.
Publication type:
Article
Transcriptional activation of Brassica napusβ-ketoacyl-ACP synthase II with an engineered zinc finger protein transcription factor.
Published in:
Plant Biotechnology Journal, 2012, v. 10, n. 7, p. 783, doi. 10.1111/j.1467-7652.2012.00695.x
By:
- Gupta, Manju;
- DeKelver, Russell C.;
- Palta, Asha;
- Clifford, Carla;
- Gopalan, Sunita;
- Miller, Jeffrey C.;
- Novak, Stephen;
- Desloover, Daniel;
- Gachotte, Daniel;
- Connell, James;
- Flook, Josh;
- Patterson, Thomas;
- Robbins, Kelly;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Petolino, Joseph F.
Publication type:
Article
Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 3, p. 1, doi. 10.1093/nar/gkv1121
By:
- Jianbin Wang;
- DeClercq, Joshua J.;
- Hayward, Samuel B.;
- Patrick Wai-Lun Li;
- Shivak, David A.;
- Gregory, Philip D.;
- Lee, Gary;
- Holmes, Michael C.
Publication type:
Article
Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.
Published in:
PLoS Pathogens, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.ppat.1005983
By:
- Leslie, George J.;
- Haggarty, Beth S.;
- Jordon, Andrea P. O.;
- Romano, Josephine;
- Kumar, Kritika E.;
- Hoxie, James A.;
- Wang, Jianbin;
- Hua, Kevin L.;
- Duong, Jennifer;
- DeClercq, Joshua J.;
- Gregory, Philip D.;
- Holmes, Michael C.;
- Richardson, Max W.;
- Riley, James L.;
- Secreto, Anthony J.;
- June, Carl H.;
- Root, Michael J.
Publication type:
Article
In vivo cleavage of transgene donors promotes nuclease-mediated targeted integration.
Published in:
Biotechnology & Bioengineering, 2013, v. 110, n. 3, p. 871, doi. 10.1002/bit.24733
By:
- Cristea, Sandra;
- Freyvert, Yevgeniy;
- Santiago, Yolanda;
- Holmes, Michael C.;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Cost, Gregory J.
Publication type:
Article
Highly efficient deletion of FUT8 in CHO cell lines using zinc-finger nucleases yields cells that produce completely nonfucosylated antibodies.
Published in:
Biotechnology & Bioengineering, 2010, v. 106, n. 5, p. 774, doi. 10.1002/bit.22751
By:
- Malphettes, Laetitia;
- Freyvert, Yevgeniy;
- Chang, Jennifer;
- Liu, Pei-Qi;
- Chan, Edmond;
- Miller, Jeffrey C.;
- Zhou, Zhe;
- Nguyen, Thu;
- Tsai, Christina;
- Snowden, Andrew W.;
- Collingwood, Trevor N.;
- Gregory, Philip D.;
- Cost, Gregory J.
Publication type:
Article
Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases.
Published in:
Biotechnology & Bioengineering, 2010, v. 106, n. 1, p. 97, doi. 10.1002/bit.22654
By:
- Liu, Pei-Qi;
- Chan, Edmond M.;
- Cost, Gregory J.;
- Zhang, Lin;
- Wang, Jianbin;
- Miller, Jeffrey C.;
- Guschin, Dmitry Y.;
- Reik, Andreas;
- Holmes, Michael C.;
- Mott, John E.;
- Collingwood, Trevor N.;
- Gregory, Philip D.
Publication type:
Article
BAK and BAX deletion using zinc-finger nucleases yields apoptosis-resistant CHO cells.
Published in:
Biotechnology & Bioengineering, 2010, v. 105, n. 2, p. 330, doi. 10.1002/bit.22541
By:
- Cost, Gregory J.;
- Freyvert, Yevgeniy;
- Vafiadis, Annamaria;
- Santiago, Yolanda;
- Miller, Jeffrey C.;
- Rebar, Edward;
- Collingwood, Trevor N.;
- Snowden, Andrew;
- Gregory, Philip D.
Publication type:
Article
Enhanced protein production by engineered zinc finger proteins.
Published in:
Biotechnology & Bioengineering, 2007, v. 97, n. 5, p. 1180, doi. 10.1002/bit.21304
By:
- Reik, Andreas;
- Zhou, Yuanyue;
- Collingwood, Trevor N.;
- Warfe, Lyndon;
- Bartsevich, Victor;
- Kong, Yanhong;
- Henning, Karla A.;
- Fallentine, Barrett K.;
- Zhang, Lei;
- Zhong, Xiaohong;
- Jouvenot, Yann;
- Jamieson, Andrew C.;
- Rebar, Edward J.;
- Case, Casey C.;
- Korman, Alan;
- Li, Xiao-Yong;
- Black, Amelia;
- King, David J.;
- Gregory, Philip D.
Publication type:
Article
Targeted gene therapy and cell reprogramming in Fanconi anemia.
Published in:
EMBO Molecular Medicine, 2014, v. 6, n. 6, p. 835, doi. 10.15252/emmm.201303374
By:
- Rio, Paula;
- Baños, Rocio;
- Lombardo, Angelo;
- Quintana‐Bustamante, Oscar;
- Alvarez, Lara;
- Garate, Zita;
- Genovese, Pietro;
- Almarza, Elena;
- Valeri, Antonio;
- Díez, Begoña;
- Navarro, Susana;
- Torres, Yaima;
- Trujillo, Juan P;
- Murillas, Rodolfo;
- Segovia, Jose C;
- Samper, Enrique;
- Surralles, Jordi;
- Gregory, Philip D;
- Holmes, Michael C;
- Naldini, Luigi
Publication type:
Article
Chromatin remodelling at the PHO8 promoter requires SWI-SNF and SAGA at a step subsequent to activator binding.
Published in:
EMBO Journal, 1999, v. 18, n. 22, p. 6407, doi. 10.1093/emboj/18.22.6407
By:
- Gregory, Philip D.;
- Schmid, Andrea;
- Zavari, Maasoumeh;
- Munsterkotter, Martin;
- Horz, Wolfram
Publication type:
Article
Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases.
Published in:
PLoS Pathogens, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.ppat.1002020
By:
- Wilen, Craig B.;
- Wang, Jianbin;
- Tilton, John C.;
- Miller, Jeffrey C.;
- Kim, Kenneth A.;
- Rebar, Edward J.;
- Sherrill-Mix, Scott A.;
- Patro, Sean C.;
- Secreto, Anthony J.;
- Jordan, Andrea P. O.;
- Lee, Gary;
- Kahn, Joshua;
- Aye, Pyone P.;
- Bunnell, Bruce A.;
- Lackner, Andrew A.;
- Hoxie, James A.;
- Danet-Desnoyers, Gwenn A.;
- Bushman, Frederic D.;
- Riley, James L.;
- Gregory, Philip D.
Publication type:
Article
Production of Ultracold 87Rb133Cs in the Absolute Ground State: Complete Characterisation of the Stimulated Raman Adiabatic Passage Transfer.
Published in:
ChemPhysChem, 2016, v. 17, n. 22, p. 3811, doi. 10.1002/cphc.201600501
By:
- Molony, Peter K.;
- Gregory, Philip D.;
- Kumar, Avinash;
- Le Sueur, C. Ruth;
- Hutson, Jeremy M.;
- Cornish, Simon L.
Publication type:
Article
Targeted genome editing in human repopulating haematopoietic stem cells.
Published in:
Nature, 2014, v. 510, n. 7504, p. 235, doi. 10.1038/nature13420
By:
- Genovese, Pietro;
- Schiroli, Giulia;
- Escobar, Giulia;
- Di Tomaso, Tiziano;
- Firrito, Claudia;
- Calabria, Andrea;
- Moi, Davide;
- Mazzieri, Roberta;
- Bonini, Chiara;
- Holmes, Michael C.;
- Gregory, Philip D.;
- van der Burg, Mirjam;
- Gentner, Bernhard;
- Montini, Eugenio;
- Lombardo, Angelo;
- Naldini, Luigi
Publication type:
Article
Translating dosage compensation to trisomy 21.
Published in:
Nature, 2013, v. 500, n. 7462, p. 296, doi. 10.1038/nature12394
By:
- Jiang, Jun;
- Jing, Yuanchun;
- Cost, Gregory J.;
- Chiang, Jen-Chieh;
- Kolpa, Heather J.;
- Cotton, Allison M.;
- Carone, Dawn M.;
- Carone, Benjamin R.;
- Shivak, David A.;
- Guschin, Dmitry Y.;
- Pearl, Jocelynn R.;
- Rebar, Edward J.;
- Byron, Meg;
- Gregory, Philip D.;
- Brown, Carolyn J.;
- Urnov, Fyodor D.;
- Hall, Lisa L.;
- Lawrence, Jeanne B.
Publication type:
Article
In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Published in:
Nature, 2011, v. 475, n. 7355, p. 217, doi. 10.1038/nature10177
By:
- Hojun Li;
- Haurigot, Virginia;
- Doyon, Yannick;
- Tianjian Li;
- Wong, Sunnie Y.;
- Bhagwat, Anand S.;
- Malani, Nirav;
- Anguela, Xavier M.;
- Sharma, Rajiv;
- Ivanciu, Lacramiora;
- Murphy, Samuel L.;
- Finn, Jonathan D.;
- Khazi, Fayaz R.;
- Shangzhen Zhou;
- Paschon, David E.;
- Rebar, Edward J.;
- Bushman, Frederic D.;
- Gregory, Philip D.;
- Holmes, Michael C.;
- High, Katherine A.
Publication type:
Article
Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Published in:
Neuro-Oncology, 2022, v. 24, n. 8, p. 1318, doi. 10.1093/neuonc/noac024
By:
- Brown, Christine E;
- Rodriguez, Analiz;
- Palmer, Joycelynne;
- Ostberg, Julie R;
- Naranjo, Araceli;
- Wagner, Jamie R;
- Aguilar, Brenda;
- Starr, Renate;
- Weng, Lihong;
- Synold, Timothy W;
- Tran, Vivi;
- Wang, Shelley;
- Reik, Andreas;
- D'Apuzzo, Massimo;
- Ressler, Julie A;
- Zhou, Yuanyue;
- Mendel, Matthew;
- Gregory, Philip D;
- Holmes, Michael C;
- Tang, Winson W
Publication type:
Article
Efficient Immunoglobulin Gene Disruption and Targeted Replacement in Rabbit Using Zinc Finger Nucleases.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021045
By:
- Flisikowska, Tatiana;
- Thorey, Irmgard S.;
- Offner, Sonja;
- Ros, Francesca;
- Lifke, Valeria;
- Zeitler, Bryan;
- Rottmann, Oswald;
- Vincent, Anna;
- Lei Zhang;
- Jenkins, Shirin;
- Niersbach, Helmut;
- Kind, Alexander J.;
- Gregory, Philip D.;
- Schnieke, Angelika E.;
- Platzer, Josef
Publication type:
Article
Dissection of Splicing Regulation at an Endogenous Locus by Zinc-Finger Nuclease-Mediated Gene Editing.
Published in:
PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016961
By:
- Cristea, Sandra;
- Gregory, Philip D.;
- Urnov, Fyodor D.;
- Cost, Gregory J.
Publication type:
Article
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer.
Published in:
Nature Medicine, 2012, v. 18, n. 5, p. 807, doi. 10.1038/nm.2700
By:
- Provasi, Elena;
- Genovese, Pietro;
- Lombardo, Angelo;
- Magnani, Zulma;
- Liu, Pei-Qi;
- Reik, Andreas;
- Chu, Victoria;
- Paschon, David E;
- Zhang, Lei;
- Kuball, Jurgen;
- Camisa, Barbara;
- Bondanza, Attilio;
- Casorati, Giulia;
- Ponzoni, Maurilio;
- Ciceri, Fabio;
- Bordignon, Claudio;
- Greenberg, Philip D;
- Holmes, Michael C;
- Gregory, Philip D;
- Naldini, Luigi
Publication type:
Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 49, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
By:
- Laganiere, Josee;
- Keils, Adrian P.;
- Lai, Jeffrey T.;
- Guschin, Dmitry;
- Paschon, David E.;
- Xiangdong Meng;
- Fong, Lauren K.;
- Qi Yu;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Bankiewicz, Krystof S.;
- Forsayeth, John;
- Zhang, H. Steve
Publication type:
Article
An Engineered Zinc Finger Protein Activator of the Endogenous Glial Cell Line-Derived Neurotrophic Factor Gene Provides Functional Neuroprotection in a Rat Model of Parkinson's Disease.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 48, p. 16469, doi. 10.1523/JNEUROSCI.2440-10.2010
By:
- Laganiere, Josee;
- Kells, Adrian P.;
- Lai, Jeffrey T.;
- Guschin, Dmitry;
- Paschon, David E.;
- Xiangdong Meng;
- Fong, Lauren K.;
- Qi Yu;
- Rebar, Edward J.;
- Gregory, Philip D.;
- Bankiewicz, Krystof S.;
- Forsayeth, John;
- Zhang, H. Steve
Publication type:
Article
Improved specificity of TALE-based genome editing using an expanded RVD repertoire.
Published in:
Nature Methods, 2015, v. 12, n. 5, p. 465, doi. 10.1038/nmeth.3330
By:
- Miller, Jeffrey C;
- Zhang, Lei;
- Xia, Danny F;
- Campo, John J;
- Ankoudinova, Irina V;
- Guschin, Dmitry Y;
- Babiarz, Joshua E;
- Meng, Xiangdong;
- Hinkley, Sarah J;
- Lam, Stephen C;
- Paschon, David E;
- Vincent, Anna I;
- Dulay, Gladys P;
- Barlow, Kyle A;
- Shivak, David A;
- Leung, Elo;
- Kim, Jinwon D;
- Amora, Rainier;
- Urnov, Fyodor D;
- Gregory, Philip D
Publication type:
Article
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.
Published in:
Nature Methods, 2012, v. 9, n. 10, p. 993, doi. 10.1038/nmeth.2143
By:
- Straimer, Judith;
- Lee, Marcus C S;
- Lee, Andrew H;
- Zeitler, Bryan;
- Williams, April E;
- Pearl, Jocelynn R;
- Zhang, Lei;
- Rebar, Edward J;
- Gregory, Philip D;
- Llinás, Manuel;
- Urnov, Fyodor D;
- Fidock, David A
Publication type:
Article
Site-specific integration and tailoring of cassette design for sustainable gene transfer.
Published in:
Nature Methods, 2011, v. 8, n. 10, p. 861, doi. 10.1038/nmeth.1674
By:
- Lombardo, Angelo;
- Cesana, Daniela;
- Genovese, Pietro;
- Di Stefano, Bruno;
- Provasi, Elena;
- Colombo, Daniele F;
- Neri, Margherita;
- Magnani, Zulma;
- Cantore, Alessio;
- Lo Riso, Pietro;
- Damo, Martina;
- Pello, Oscar M;
- Holmes, Michael C;
- Gregory, Philip D;
- Gritti, Angela;
- Broccoli, Vania;
- Bonini, Chiara;
- Naldini, Luigi
Publication type:
Article
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.
Published in:
Nature Methods, 2011, v. 8, n. 1, p. 74, doi. 10.1038/nmeth.1539
By:
- Doyon, Yannick;
- Vo, Thuy D.;
- Mendel, Matthew C.;
- Greenberg, Shon G.;
- Jianbin Wang;
- Xia, Danny F.;
- Miller, Jeffrey C.;
- Urnov, Fyodor D.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article
Transient cold shock enhances zinc-finger nuclease–mediated gene disruption.
Published in:
Nature Methods, 2010, v. 7, n. 6, p. 459, doi. 10.1038/nmeth.1456
By:
- Doyon, Yannick;
- Choi, Vivian M.;
- Xia, Danny F.;
- Vo, Thuy D.;
- Gregory, Philip D.;
- Holmes, Michael C.
Publication type:
Article

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