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- Title
Rediscovering plant-based drugs.
- Authors
Littleton, John; Falcone, Deane; Davies, H. Maelor
- Abstract
However, there is a new and much more compelling reason to reexamine the medicinal potential of the plant kingdom, namely the emergence of plant genomics. This article surmises that the implications of the genomics revolution for natural products research have yet to be fully appreciated by the pharmaceutical industry narrowly focused in an emerging area. The subsequent emergence of a range of genomic and proteomic tools, many applicable to plants and not requiring complete genome sequencing, suggests that we may soon begin to achieve this goal, effectively launching a new era in pharmacological bioprospecting in the plant kingdom. People have started realizing the metabolic potential in plants, which may be activated by pathogens, climactic conditions and diverse kinds of stress. Herein lies the greatest potential of genomics, namely, the ability to survey the metabolic repertoire of a plant on a small, single tissue sample.
- Subjects
PHYTOTHERAPY; MEDICINAL plants; GENOMICS; PROTEOMICS
- Publication
Nature Biotechnology, 2003, Vol 21, Issue 8, p843
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt0803-843b