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- Title
Design and Synthesis of Phenoxypyridyl Acetamide or Aryl-oxodihydropurine Derivatives for the Development of Novel PET Ligands Targeting the Translocator Protein 18 kDa ( TSPO).
- Authors
Lee, Jihye; Jung, Jae Ho; Lee, Byung Chul; Lee, Sang-Yoon
- Abstract
The article discusses a study on the synthesis and design of phenoxypyridyl acetamide and aryl-oxodihydropurine derivatives for the development of positron emission tomography (PET) ligands targeting translocator protein 18 kDa (TSPO). Topics include the medical and clinical uses of PET ligands, the binding affinity of the derivatives and their chemical and biological properties.
- Subjects
ACETAMIDE derivatives; CHEMICAL synthesis; POSITRON emission tomography; PHENOXY compounds; TRANSLOCATOR proteins; PROTEIN binding
- Publication
Bulletin of the Korean Chemical Society, 2016, Vol 37, Issue 11, p1874
- ISSN
0253-2964
- Publication type
Article
- DOI
10.1002/bkcs.10979