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- Title
The Investigation of Plasma Glucagon-like Peptide-1 Levels in Newly Diagnosed Type 1 Diabetic Children.
- Authors
Uslu, B.; Gurbuz, F.; Temiz, F.; Yuksel, B.; Mungan, N.; Topaloglu, A. K.
- Abstract
Objective: To reveal the possible role of glucagon-like peptide-1 (GLP-1) in newly diagnosed Type 1 diabetic children. Methods: Twenty-five newly diagnosed children and 22 healthy children were included in the study. Results: In oral glucose tolerance tests, no correlation was observed between C-peptide and GLP-1 levels at 0 and 30 minutes, and plasma GLP-1 levels in both groups at 0 and 30 minutes were not statistically different. Conclusion: Consequently, fasting and postprandial GLP-1 levels in newly diagnosed Type 1 diabetic children are not different from healthy children. Glucagon-like peptide-1 levels in newly diagnosed Type 1 diabetic children suggest that plasma GLP-1 levels do not have any role in the pathogenesis of Type 1 diabetes mellitus.
- Subjects
DIABETES in children; TYPE 1 diabetes; CHILDREN'S health; GLUCOSE tolerance tests; DIAGNOSIS; PATIENTS; THERAPEUTICS
- Publication
West Indian Medical Journal, 2016, Vol 65, Issue 1, p141
- ISSN
0043-3144
- Publication type
Article
- DOI
10.7727/wimj.2014.134