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- Title
Recent Advances in Genetic Technique of Microbial Report Cells and Their Applications in Cell Arrays.
- Authors
Kim, Do Hyun; Kim, Moon Il; Park, Hyun Gyu
- Abstract
Microbial cell arrays have attracted consistent attention for their ability to provide unique global data on target analytes at low cost, their capacity for readily detectable and robust cell growth in diverse environments, their high degree of convenience, and their capacity for multiplexing via incorporation of molecularly tailored reporter cells. To highlight recent progress in the field of microbial cell arrays, this review discusses research on genetic engineering of reporter cells, technologies for patterning live cells on solid surfaces, cellular immobilization in different polymers, and studies on their application in environmental monitoring, disease diagnostics, and other related fields. On the basis of these results, we discuss current challenges and future prospects for novel microbial cell arrays, which show promise for use as potent tools for unraveling complex biological processes.
- Subjects
GENETIC techniques; TISSUE arrays; MICROBIAL cells; CELL growth; BIOSENSORS; BIOAVAILABILITY; GENETIC engineering
- Publication
BioMed Research International, 2015, Vol 2015, p1
- ISSN
2314-6133
- Publication type
journal article
- DOI
10.1155/2015/182107