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- Title
Bone marrow cell transplantation improves cardiac, autonomic, and functional indexes in acute anterior myocardial infarction patients (Cardiac Study).
- Authors
Piepoli, Massimo F.; Vallisa, Daniele; Arbasi, Mariacristina; Cavanna, Luigi; Cerri, Luigi; Mori, Monica; Passerini, Francesco; Tommasi, Luigi; Rossi, Agostino; Capucci, Alessandro
- Abstract
Aims: Bone marrow (BM) stem cells improve cardiac function and outcome after acute ST-segment elevation myocardial infarction (MI). In this randomized controlled trial, the effects of intracoronary transfer of autologous BM cells on left ventricular ejection fraction (LVEF) and volumes (2D-echo and resting SPECT), stroke volume [impedance cardiography (ICG)], autonomic control [heart rate variability (HRV)], baroreflex sensitivity (BRS), and exercise tolerance (cardiopulmonary exercise test) were assessed in post-MI patients. Exercise stress SPECT was also performed.
- Subjects
NEOVASCULARIZATION; BONE marrow; MYOCARDIAL infarction; REPERFUSION; CLINICAL trials
- Publication
European Journal of Heart Failure, 2010, Vol 12, Issue 2, p172
- ISSN
1388-9842
- Publication type
Article
- DOI
10.1093/eurjhf/hfp183