We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effects of the XRCC1 Gene-Environment Interactions on DNA Damage in Healthy Japanese Workers.
- Authors
Zuquan Weng; Yuquan Lu; Huachuan Weng; Morimoto, Kanehisa
- Abstract
The article presents a study on the relation between XRCC1 gene-environment interactions and DNA damage in healthy Japanese workers. The research involves a data analysis of gene polymorphisms and their possible interactions with smoking, drinking habits, age, and health practice index (HPI). It shows that poor HPI is associated with a higher level of tail moment (TM) values which were enhanced by alcohol consumption and aging. It indicates that a stratified analysis suggests that XRCC1 polymorphisms influence the individual DNA repair capacity by interacting with lifestyle factors.
- Subjects
JAPAN; GENOTYPE-environment interaction; DNA damage; BIOCHEMICAL genetics; GENETICS; GENETIC polymorphisms; SMOKING; ALCOHOL drinking; AGING
- Publication
Environmental & Molecular Mutagenesis, 2008, Vol 49, Issue 9, p708
- ISSN
0893-6692
- Publication type
Article
- DOI
10.1002/em.20421