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- Title
Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome.
- Authors
Oh, Mi; Ham, Byeong; Kang, Seok; Bae, Jae; Kim, Je; Yoo, Ki; Yoon, Duck; Moon, Du
- Abstract
Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.
- Subjects
CASE studies; LESCH-Nyhan syndrome; TREATMENT of calculi; URINE; URIC acid; JUVENILE diseases
- Publication
Urological Research, 2011, Vol 39, Issue 5, p417
- ISSN
0300-5623
- Publication type
Report
- DOI
10.1007/s00240-011-0364-z