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- Title
An approximate estimate of the ion-activity product of calcium oxalate in rat urine.
- Authors
Tiselius, Hans-Göran; Ferraz, Renato Ribeiro Nogueira; Heilberg, Ita Pfeferman
- Abstract
The objective of this report was to derive a simplified approximate estimate of the ion-activity product of calcium oxalate (APCaOx) in rat urine. The relative effect of each urine variable was assessed by means of iterative computerised approximation with the EQUIL2 program. A basic urine composition was chosen from literature and experimental data. The most pronounced influence on APCaOx was recorded for urinary calcium, oxalate, citrate, magnesium and volume. Based on these calculations, an AP(CaOx) indexRAT was formulated: A-Calcium0:93Oxalate0.:96/(Citrate+F)0.60Magnesium0:.55Volume0.99. For a 24-h urine sample, factor A takes the value 4067 and factor F should be set to 0.015. Conclusion. A simplified approximate estimate of APCaOx was derived for rat urine. There was a reasonably good correspondence between AP(CaOx) indexRATand APCaOx, as derived from EQUIL2 (r=0.890), provided the other urine variables do not deviate very much from that in the basic composition.
- Subjects
CALCIUM oxalate; URINE; URINALYSIS; RATS; IONS; CITRATES
- Publication
Urological Research, 2003, Vol 31, Issue 6, p410
- ISSN
0300-5623
- Publication type
Article
- DOI
10.1007/s00240-003-0363-9